Relationship Between Muscle Tone and Elasticity: Simultaneous Quantitative Assessment Using Train-of-Four Monitoring and Continuous Shear Wave Elastography During Anesthesia Induction-A Prospective Observational Study

被引：0

作者：

Shitara, Hitoshi ^{[1
]}

Hiroki, Tadanao ^{[2
]}

Koda, Ren ^{[3
]}

Sasaki, Tsuyoshi ^{[1
]}

Kamiyama, Masataka ^{[1
]}

Miyamoto, Ryosuke ^{[1
]}

Nakase, Kurumi ^{[1
]}

Ino, Fukuhisa ^{[1
]}

Kachi, Takuma ^{[1
]}

Mieda, Rie ^{[2
]}

Aso, Chizu ^{[2
]}

Yamakoshi, Yoshiki ^{[3
,4
]}

Saito, Shigeru ^{[2
]}

Chikuda, Hirotaka ^{[1
]}

机构：

[1] Gunma Univ, Grad Sch Med, Dept Orthopaed Surg, 3-39-15 Showa Machi, Maebashi 3718511, Japan

[2] Gunma Univ, Grad Sch Med, Dept Anesthesiol, 3-39-22 Showa Machi, Maebashi 3718511, Japan

[3] Gunma Univ, Grad Sch Sci & Technol, 1-5-1 Tenjin Cho, Kiryu 3768515, Japan

[4] Inst Sci Tokyo, Inst Innovat Res, 4259 R2-25,Nagatsuta Cho,Midori Ku, Yokohama 2268503, Japan

来源：

DIAGNOSTICS | 2025年 / 15卷 / 03期

关键词：

shear wave elastography (SWE); train-of-four (TOF) monitoring; anesthesia induction; vastus lateralis; ACOUSTIC RADIATION FORCE; STIFFNESS; RISE;

D O I：

10.3390/diagnostics15030293

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background/Objectives: Non-invasive evaluations of muscle elasticity and tone are crucial in musculoskeletal medicine. Shear wave elastography (SWE) provides quantitative assessments of muscle elasticity, whereas train-of-four (TOF) monitoring measures muscle tone during neuromuscular blockades. This study investigated the relationship between muscle elasticity and tone during anesthesia induction using continuous SWE (C-SWE) and TOF monitoring. Methods: Fifteen patients who underwent general anesthesia with rocuronium were recruited. The muscle elasticity of the vastus lateralis was assessed using C-SWE, and muscle tone was evaluated using TOF monitoring. Measurements were taken at two time points: before rocuronium administration and during complete muscle relaxation, confirmed by the TOF ratio (TOF = 0). Statistical analyses were performed using paired t-tests and correlation analyses. Results: Data from 11 patients were analyzed. The mean shear wave velocity (SWV) decreased significantly from 5.0 +/- 0.4 m/s before rocuronium administration to 3.1 +/- 0.3 m/s during complete relaxation (p < 0.0001). A significant negative correlation was observed between the baseline SWV and the degree of reduction in the SWV (r = -0.728, p = 0.011). No significant correlations were found between SWV and demographic factors such as age, sex, height, or body mass index. Conclusions: C-SWE and TOF monitoring are reliable and sensitive methods for evaluating muscle elasticity and tone during general anesthesia. This study highlights the interplay between muscle tone and elasticity, suggesting that muscles with a higher baseline tone exhibit a greater reduction in elasticity after relaxation. These findings have implications for improving intraoperative muscle function assessments and advancing the application of C-SWE in clinical practice.

引用

页数：13

共 27 条

[1] Ryu J., Jeong W.K., Current status of musculoskeletal application of shear wave elastography, Ultrasonography, 36, pp. 185-197, (2017)
[2] Taljanovic M.S., Gimber L.H., Becker G.W., Latt L.D., Klauser A.S., Melville D.M., Gao L., Witte R.S., Shear-wave elastography: Basic physics and musculoskeletal applications, RadioGraphics, 37, pp. 855-870, (2017)
[3] Chowdhary K., Raum G., Visco C., Diagnostic utility of shear wave elastography in musculoskeletal injuries: A narrative review, PM&R, 16, pp. 384-397, (2024)
[4] Haueise A., Le Sant G., Eisele-Metzger A., Dieterich A.V., Is musculoskeletal pain associated with increased muscle stiffness? Evidence map and critical appraisal of muscle measurements using shear wave elastography, Clin. Physiol. Funct. Imaging, 44, pp. 187-204, (2024)
[5] Kuo W.H., Jian D.W., Wang T.G., Wang Y.C., Neck muscle stiffness quantified by sonoelastography is correlated with body mass index and chronic neck pain symptoms, Ultrasound Med. Biol, 39, pp. 1356-1361, (2013)
[6] Nightingale K., McAleavey S., Trahey G., Shear-wave generation using acoustic radiation force: In vivo and ex vivo results, Ultrasound Med. Biol, 29, pp. 1715-1723, (2003)
[7] Regueme S.C., Frulio N., Trillaud H., Laurent C., Rullier E., Dallaudiere B., Bourdel-Marchasson I., Acoustic radiation force impulse elastography: A tool for muscle aging assessment: A pilot study, JCSM Rapid Commun, 4, pp. 133-140, (2021)
[8] Herman B.A., Harris G.R., Models and regulatory considerations for transient temperature rise during diagnostic ultrasound pulses, Ultrasound Med. Biol, 28, pp. 1217-1224, (2002)
[9] Nitta N., Ishiguro Y., Sasanuma H., Takayama N., Rifu K., Taniguchi N., Akiyama I., In vivo temperature rise measurements of rabbit liver and femur bone surface exposed to an acoustic radiation force impulse, Ultrasound Med. Biol, 48, pp. 1240-1255, (2022)
[10] Qiao Y., Zou C., Cheng C., Tie C., Wan Q., Peng H., Liang D., Liu X., Zheng H., Simultaneous acoustic radiation force imaging and MR thermometry based on a coherent echo-shifted sequence, Quant. Imaging Med. Surg, 10, pp. 1823-1836, (2020)

← 1 2 3 →