Potential Mechanisms of Covid-19 Related Nervous System Damage and Effects on Female Fertility

被引：0
作者：
Qian, Chen-yue [1 ]
Hu, Si-ning [2 ]
Liu, Huadong [1 ,3 ,4 ,5 ,6 ,7 ]
Liu, Jing-jin [1 ,3 ,4 ,5 ,6 ,7 ]
机构：
[1] Jinan Univ, Clin Med Coll 2, Shenzhen, Guangdong, Peoples R China
[2] Harbin Med Univ, Affiliated Hosp 2, Dept Cardiol, Key Labs Educ Minist Myocardial Ischemia, Harbin, Heilongjiang, Peoples R China
[3] Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Dept Cardiol, Shenzhen, Guangdong, Peoples R China
[4] Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen, Guangdong, Peoples R China
[5] Jinan Univ, Clin Med Coll 2, Shenzhen Peoples Hosp, Dept Cardiol,Shenzhen Cardiovasc Minimally Invas M, Shenzhen, Guangdong, Peoples R China
[6] Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Shenzhen Key Lab Stem Cell Res & Clin Transformat, Shenzhen, Guangdong, Peoples R China
[7] Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Geriatr,Clin Med Coll 2, Shenzhen, Guangdong, Peoples R China
来源：
CURRENT MEDICINAL CHEMISTRY | 2024年
关键词：
COVID-19; central nervous system; immune response; fertility; pharmacological treatment; ORTHOSTATIC TACHYCARDIA SYNDROME; CORONAVIRUS INFECTION; OXIDATIVE STRESS; ANGIOTENSIN-II; EXPRESSION; BASIGIN; ACTIVATION; DIAGNOSIS; RECEPTOR; ACE2;
D O I：
10.2174/0109298673333968241011092801
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Signs and symptoms that persist or worsen beyond the "acute COVID-19" stage are referred to as long-COVID. These patients are more likely to suffer from multiple organ failure, readmission, and mortality. According to a recent theory, long-lasting COVID-19 symptoms may be caused by abnormal autonomic nervous system (ANS) activity, such as hypovolemia, brain stem involvement, and autoimmune reactions. Furthermore, COVID-19 can also cause impaired fertility in women, which may also be related to inflammation and immune responses. Currently, few treatments are available for long-COVID symptoms. This article reviews the major effects of COVID-19 on the nervous system and female fertility, as well as offers potential treatment approaches.
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页数：15
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