Frozen in Time: Intraoperative Diagnosis and Management of Malignant Transformation in Mature Cystic Teratoma

被引：0
作者：
Sanap, Arun Sudhakar [1 ]
Davile, Medha D. [1 ]
Kamath, Anusha A. [1 ]
Mundle, Shuchita R. [1 ]
机构：
[1] AIIMS, Dept Obstet & Gynecol, Nagpur, Maharashtra, India
来源：
JOURNAL OF MID-LIFE HEALTH | 2024年 / 15卷 / 02期
关键词：
Frozen section; malignant transformation; mature cystic teratoma; postmenopausal; squamous cell carcinoma; SQUAMOUS-CELL CARCINOMA;
D O I：
10.4103/jmh.jmh_253_23
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Malignant transformation (MCT) of ovary is rare complications affecting elderly, squamous cell carcinoma being the most common. The prognosis worsens with extraovarian spread. We present two cases of MCT-derived SCC. Patients exhibited abdominal lump, pain, bowel symptoms, sometimes with weight loss; imaging revealed MCT. Age (51-60), postmenopausal status, large size (>20 cm), bilaterality, and complex ovarian lesions raised suspicion of malignancy. Elevated tumor markers (e.g., cancer antigen-125 and lactate dehydrogenase) were noted in one case. Intraoperative frozen section confirmed malignancy, guiding staging laparotomy. One case was advanced stage on histopathology. Intraoperative frozen section aids optimal staging.
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收藏
页码：115 / 118
页数：4
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