Report on the 6th Ottawa International Conference on Neuromuscular Disease & Biology - September 7-9, 2023, Ottawa, Canada

被引:0
作者
Warman-Chardon, Jodi [1 ,2 ,3 ,4 ,5 ,6 ]
Jasmin, Bernard J. [5 ,6 ]
Kothary, Rashmi [1 ,2 ,5 ,6 ,7 ,8 ]
Parks, Robin J. [1 ,2 ,5 ,7 ,8 ]
机构
[1] Ottawa Hosp, Dept Med, Ottawa, ON, Canada
[2] Univ Ottawa, Ottawa, ON, Canada
[3] Childrens Hosp Eastern Ontario, Dept Genet, Ottawa, ON, Canada
[4] Ottawa Hosp Res Inst, Neurosci Program, Ottawa, ON, Canada
[5] Univ Ottawa, Ctr Neuromuscular Dis, Ottawa, ON, Canada
[6] Univ Ottawa, Dept Cellular & Mol Med, Ottawa, ON, Canada
[7] Ottawa Hosp Res Inst, Regenerat Med Program, Ottawa, ON, Canada
[8] Univ Ottawa, Dept Biochem Microbiol & Immunol, Ottawa, ON, Canada
基金
加拿大健康研究院;
关键词
neuromuscular; conference; NMD; muscle; stem cell; BECKER MUSCULAR-DYSTROPHY; GENE-THERAPY; MUSCLE MRI; DUCHENNE; DIAGNOSIS; MULTICENTER; PREVALENCE; MYOPATHIES; MANAGEMENT; DISORDERS;
D O I
10.1177/22143602241304993
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The 6th Ottawa International Conference in Neuromuscular Disease and Biology was held on September 7-9, 2023 in Ottawa, Canada. The goal of the conference was to assemble international experts in fundamental science, translational medicine and clinical neuromuscular disease research. Speakers provided attendees with updates on a wide range of topics related to neuromuscular disease and biology, including methods to identify novel diseases, recent developments in muscle, motor neuron and stem cell biology, expanded disease pathogenesis of known diseases, and exciting advances in therapy development. A summary of the major topics and results presented by these speakers is provided.
引用
收藏
页码:102 / 115
页数:14
相关论文
共 129 条
  • [61] Highly Elevated Prevalence of Spinobulbar Muscular Atrophy in Indigenous Communities in Canada Due to a Founder Effect
    Leckie, Jamie N.
    Joel, Matthew M.
    Martens, Kristina
    King, Alexandra
    King, Malcolm
    Korngut, Lawrence W.
    de Koning, A. P. Jason
    Pfeffer, Gerald
    Schellenberg, Kerri L.
    [J]. NEUROLOGY-GENETICS, 2021, 7 (04)
  • [62] Congenital tremor and myopathy secondary to novel MYBPC1 variant
    Leduc-Pessah, Heather
    Smith, Ian C.
    Kernohan, Kristin D.
    Sampaio, Marcos
    Melkus, Gerd
    Strasser, Lauren
    Chisholm, Caitlin
    Huang, Lijia
    Hanes, Ilana
    Tran, My-An
    Venkateswaran, Sunita
    Muir, Katherine
    Charlesworth, Laurel
    Warman-Chardon, Jodi
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2024, 457
  • [63] Death after High-Dose rAAV9 Gene Therapy in a Patient with Duchenne's Muscular Dystrophy
    Lek, Angela
    Wong, Brenda
    Keeler, Allison
    Blackwood, Meghan
    Ma, Kaiyue
    Huang, Shushu
    Sylvia, Katelyn
    Batista, A. Rita
    Artinian, Rebecca
    Kokoski, Danielle
    Parajuli, Shestruma
    Putra, Juan
    Carreon, C. Katte
    Lidov, Hart
    Woodman, Keryn
    Pajusalu, Sander
    Spinazzola, Janelle M.
    Gallagher, Thomas
    Larovere, Joan
    Balderson, Diane
    Black, Lauren
    Sutton, Keith
    Horgan, Richard
    Lek, Monkol
    Flotte, Terence
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2023, 389 (13) : 1203 - 1210
  • [64] Autosomal dominant in cis D4Z4 repeat array duplication alleles in facioscapulohumeral dystrophy
    Lemmers, Richard J. L. F.
    Butterfield, Russell
    van der Vliet, Patrick J.
    de Bleecker, Jan L.
    van der Pol, Ludo
    Dunn, Diane M.
    Erasmus, Corrie E.
    D'Hooghe, Marc
    Verhoeven, Kristof
    Balog, Judit
    Bigot, Anne
    van Engelen, Baziel
    Statland, Jeffrey
    Bugiardini, Enrico
    van der Stoep, Nienke
    Evangelista, Teresinha
    Marini-Bettolo, Chiara
    van den Bergh, Peter
    Tawil, Rabi
    Voermans, Nicol C.
    Vissing, John
    Weiss, Robert B.
    van der Maarel, Silvere M.
    [J]. BRAIN, 2024, 147 (02) : 414 - 426
  • [65] Comprehensive functional characterization of SGCB coding variants predicts pathogenicity in limb-girdle muscular dystrophy type R4/2E
    Li, Chengcheng
    Wilborn, Jackson
    Pittman, Sara
    Daw, Jil
    Alonso-Perez, Jorge
    Diaz-Manera, Jordi
    Weihl, Conrad C.
    Haller, Gabe
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2023, 133 (12)
  • [66] Current and Future Approaches to Classify VUSs in LGMD-Related Genes
    Li, Chengcheng
    Haller, Gabe
    Weihl, Conrad C.
    [J]. GENES, 2022, 13 (02)
  • [67] Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse
    Mann, CJ
    Honeyman, K
    Cheng, AJ
    Ly, T
    Lloyd, F
    Fletcher, S
    Morgan, JE
    Partridge, TA
    Wilton, SD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (01) : 42 - 47
  • [68] Beyond motor neurons: expanding the clinical spectrum in Kennedy's disease
    Manzano, Raquel
    Soraru, Gianni
    Grunseich, Christopher
    Fratta, Pietro
    Zuccaro, Emanuela
    Pennuto, Maria
    Rinaldi, Carlo
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2018, 89 (08) : 808 - 812
  • [69] Properties of Glial Cell at the Neuromuscular Junction Are Incompatible with Synaptic Repair in the SOD1G37R ALS Mouse Model
    Martineau, Eric
    Arbour, Danielle
    Vallee, Joanne
    Robitaille, Richard
    [J]. JOURNAL OF NEUROSCIENCE, 2020, 40 (40) : 7759 - 7777
  • [70] Quantitative vs qualitative muscle MRI: Imaging biomarker in patients with Oculopharyngeal Muscular Dystrophy (OPMD)
    Melkus, Gerd
    Sampaio, Marcos L.
    Smith, Ian C.
    Rakhra, Kawan S.
    Bourque, Pierre R.
    Breiner, Ari
    Zwicker, Jocelyn
    Lochmueller, Hanns
    Brais, Bernard
    Warman-Chardon, Jodi
    [J]. NEUROMUSCULAR DISORDERS, 2023, 33 (01) : 24 - 31