Evidence of Clinical and Laboratory Correlation of Itraconazole Resistance in Sporothrix brasiliensis Infection: Case Report

被引：1

作者：

Veasey, John Verrinder ^{[1
]}

Reis, Ana Paula Carvalho ^{[2
]}

Celestrino, Giovanna Azevedo ^{[2
]}

Silva, Camila Estacia ^{[2
]}

Santos, Eduarda Souza ^{[2
]}

Mendes, Denise Polizel ^{[2
]}

Andrade, Tania Sueli ^{[3
]}

Bonfietti, Lucas Xavier ^{[4
]}

Benard, Gil ^{[2
]}

Sousa, Maria Gloria Texeira ^{[2
]}

机构：

[1] Santa Casa de Sao Paulo, Sch Med Sci, BR-01221010 Sao Paulo, Brazil

[2] Univ Sao Paulo, Lab Med Mycol LIM 53, Clin Dermatol Div, Hosp Clin FMUSP,Fac Med FMUSP,Inst Trop Med, BR-05403000 Sao Paulo, Brazil

[3] Secretary Hlth, Adolfo Lutz Inst, Dept Culture Collect, BR-01246000 Sao Paulo, Brazil

[4] Mycol Nucl Inst Adolfo Lutz, Hlth Dept, BR-01246000 Sao Paulo, Brazil

来源：

MICROORGANISMS | 2024年 / 12卷 / 11期

关键词：

antifungal resistance; Sporotrichosis; itraconazole; Sporothrix brasiliensis; SPOROTRICHOSIS;

D O I：

10.3390/microorganisms12112132

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Sporotrichosis is a subcutaneous infection caused by fungi from the genus Sporothrix, among which Sporothrix brasiliensis displays high virulence and transmissibility. So far, classical antifungal agents have been efficient against S. brasiliensis, but here we describe the first case of therapeutic failure and a high minimum inhibitory concentration (MIC) in relation to itraconazole.

引用

页数：5

共 14 条

[1] Minimal inhibitory concentration distributions and epidemiological cutoff values of five antifungal agents against Sporothrix brasiliensis [J].

Almeida-Paes, Rodrigo ;

Brito-Santos, Fabio ;

Galdino Figueiredo-Carvalho, Maria Helena ;

Machado, Caroline Sa ;

Evangelista Oliveira, Manoel Marques ;

Pereira, Sandro Antonio ;

Gutierrez-Galhardo, Maria Clara ;

Zancope-Oliveira, Rosely Maria .

MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2017, 112 (05) :376-381

[2] Sporotrichosis Caused by Non-Wild Type Sporothrix brasiliensis Strains [J].

Bernardes-Engemann, Andrea Reis ;

Tomki, Gabriela Ferreira ;

Rabello, Vanessa Brito de Souza ;

Almeida-Silva, Fernando ;

Freitas, Dayvison Francis Saraiva ;

Gutierrez-Galhardo, Maria Clara ;

Almeida-Paes, Rodrigo ;

Zancope-Oliveira, Rosely Maria .

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 12

[3] Susceptibility of Sporothrix brasiliensis isolates to amphotericin B, azoles, and terbinafine [J].

Borba-Santos, Luana Pereira ;

Rodrigues, Anderson Messias ;

Gagini, Thalita Braga ;

Fernandes, Geisa Ferreira ;

Castro, Rafaela ;

de Camargo, Zoilo Pires ;

Nucci, Marcio ;

Lopes-Bezerra, Leila Maria ;

Ishida, Kelly ;

Rozental, Sonia .

MEDICAL MYCOLOGY, 2015, 53 (02) :178-188

[4] Chromoblastomycosis in the Amazon region, Brazil, caused by Fonsecaea pedrosoi, Fonsecaea nubica, and Rhinocladiella similis: Clinicopathology, susceptibility, and molecular identification [J].

de Andrade, Tania Sueli ;

Zimmer de Almeida, Ana Maria ;

Basano, Sergio de Almeida ;

Takagi, Elizabeth Harummyy ;

Szeszs, Maria Walderez ;

Melhem, Marcia S. C. ;

Albuquerque, Madson ;

Almeida Aranha Camargo, Juliana de Souza ;

Gambale, Walderez ;

Aranha Camargo, Luis Marcelo .

MEDICAL MYCOLOGY, 2020, 58 (02) :172-180

[5] Seasonality of sporotrichosis in Brazil: A modelled analysis of the epidemic in Sao Paulo, 2011-2020 [J].

de Freitas, Vera Lucia Teixeira ;

Rocha, Francisco Marcelo Monteiro ;

Ribeiro, Emanoella Nogueira ;

Lindoso, Jose Angelo Laulleta ;

Bittencourt, Amanda Azevedo ;

Pivetta, Dhara Nicole Araujo Greco ;

Benard, Gil ;

de Freitas-Xavier, Roseli Santos .

MYCOSES, 2023, 66 (08) :643-650

[6]

Espinel-Ingroff A, 2017, ANTIMICROB AGENTS CH, V61, DOI [10.1128/aac.01057-17, 10.1128/AAC.01057-17]

[7] Phenotypic and Molecular Identification of Sporothrix Isolates from an Epidemic Area of Sporotrichosis in Brazil [J].

Evangelista Oliveira, Manoel Marques ;

Almeida-Paes, Rodrigo ;

Muniz, Mauro Medeiros ;

Gutierrez-Galhardo, Maria Clara ;

Zancope-Oliveira, Rosely Maria .

MYCOPATHOLOGIA, 2011, 172 (04) :257-267

[8] Severe Sporotrichosis Caused by Sporothrix brasiliensis: Antifungal Susceptibility and Clinical Outcomes [J].

Fichman, Vivian ;

Almeida-Silva, Fernando ;

Freitas, Dayvison Francis Saraiva ;

Zancope-Oliveira, Rosely Maria ;

Gutierrez-Galhardo, Maria Clara ;

Almeida-Paes, Rodrigo .

JOURNAL OF FUNGI, 2023, 9 (01)

[9]

Giske CG, 2022, J CLIN MICROBIOL, V60, DOI [10.1128/jcm.00276-21, 10.1128/JCM.00276-21]

[10] Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide [J].

Lyra, Marcelo Rosandiski ;

Sokoloski, Vanessa ;

de Macedo, Priscila Marques ;

Procopio de Azevedo, Anna Carolina .

ANAIS BRASILEIROS DE DERMATOLOGIA, 2021, 96 (02) :231-233

← 1 2 →