You better keep an eye on your contacts

被引:0
作者
Balla, Tamas [1 ]
Gulyas, Gergo [1 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Huma, Sect Mol Signal Transduct, NIH, Bethesda, MD 20892 USA
关键词
Membrane contact sites; Calcium signaling; Lipid droplets; Mitochondria; Lipid transfer;
D O I
10.1016/j.ceca.2025.102999
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Membrane contact sites (MCS) are specialized compartments found in all eukaryotic cells that are formed between membranes of different organelles that are in close proximity. MCS have important functions as they are sites of efficient transfer of molecules between neighboring organelles. Two recent articles have used the splitFAST system to mark and follow the dynamics of membrane contact sites and used the method to highlight the importance of MCS between the endoplasmic reticulum (ER) and lipid droplets in metabolic adaptation and MCS between the ER and mitochondria in Ca2+ signal propagation.
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页数:2
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