Visible-light promoted radical coupling of difluoroenol silyl ethers and difluorinated Pyf-sulfides to construct tetrafluoroethylene-containing compounds

被引:0
作者
Wang, Chen [1 ]
Wang, Zhihua [1 ]
Zhang, Jinliang [1 ]
Mu, Miaomiao [2 ,3 ]
Zhang, Jin [2 ,3 ]
Wang, Zhiming [2 ,3 ]
Yang, Jianguo [2 ,3 ]
Huang, Guobo [2 ,3 ]
Zhu, Xiaolei [2 ,3 ]
机构
[1] Zhejiang Lepu Pharmaceut Co Ltd, 29 Binhai Rd, Taizhou, Zhejiang, Peoples R China
[2] Taizhou Univ, Adv Res Inst, Jiaojiang 318000, Zhejiang, Peoples R China
[3] Taizhou Univ, Sch Pharmaceut Sci, Jiaojiang 318000, Zhejiang, Peoples R China
关键词
Visible-light; Radical coupling; Difluoroenol silyl ethers; Sulfides; FLUORINATED SULFONES; TRIFLUOROMETHYLATION; DIFLUOROALKYLATION; FLUOROALKYLATION; PHARMACEUTICALS; SULFOXIDES; ALCOHOLS; ACCESS;
D O I
10.1016/j.tetlet.2025.155505
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A visible-light promoted radical coupling of difluoroenol silyl ethers and difluorinated Pyf-sulfides has been developed. This protocol provides a simple and straightforward approach to assemble diverse functionalized tetrafluoroethylene-containing compounds in moderate to good yields.
引用
收藏
页数:6
相关论文
共 43 条
  • [1] ORGANOPHOSPHORUS CHEMISTRY .1. REACTION OF PHOSPHINE WITH FLUORO-OLEFINS
    BURCH, GM
    GOLDWHITE, H
    HASZELDINE, RN
    [J]. JOURNAL OF THE CHEMICAL SOCIETY, 1963, (FEB): : 1083 - &
  • [2] Development of (2-bromo-1,1,2,2-tetrafluoroethyl)(phenyl)sulfane as tetrafluoroethyl-radical and tetrafluoroethylene-diradical synthons for additions to alkenes
    Chernykh, Yana
    Beier, Petr
    [J]. JOURNAL OF FLUORINE CHEMISTRY, 2013, 156 : 307 - 313
  • [3] Eisuke Y., 2023, Chem. Sci., V14, P12379
  • [4] Direct addition of fluorine to arylacetylenes
    Gatenyo, Julia
    Rozen, Shlomo
    [J]. JOURNAL OF FLUORINE CHEMISTRY, 2009, 130 (03) : 332 - 335
  • [5] Direct benzylic C-H difluoroalkylation with difluoroenoxysilanes by transition metal-free photoredox catalysis
    Gui, Jing
    Sun, Manman
    Wu, Haijian
    Li, Jinshan
    Yang, Jianguo
    Wang, Zhiming
    [J]. ORGANIC CHEMISTRY FRONTIERS, 2022, 9 (17): : 4569 - 4574
  • [6] FREE RADICAL ADDITION OF TRIFLUOROMETHANETHIOL TO FLUOROOLEFINS
    HARRIS, JF
    STACEY, FW
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1961, 83 (04) : 840 - &
  • [7] Hiroki S., 2014, J. Am. Chem. Soc., V136, P15158
  • [8] Hu J. -B., 2009, Chem. Commun., V48
  • [9] Fluoroalkyl sulfides as photoredox-active coupling reagents for alkene difunctionalization
    Kosobokov, Mikhail D.
    Zubkov, Mikhail O.
    Levin, Vitalij V.
    Kokorekin, Vladimir A.
    Dilman, Alexander D.
    [J]. CHEMICAL COMMUNICATIONS, 2020, 56 (66) : 9453 - 9456
  • [10] A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes
    Le, Chip
    Chen, Tiffany Q.
    Liang, Tao
    Zhang, Patricia
    MacMillan, David W. C.
    [J]. SCIENCE, 2018, 360 (6392) : 1010 - +