Risk Factors for Suicide Among Head and Neck Cancer Patients: A Systematic Review and Meta-Analysis

被引:1
作者
Nassar, Sami I. [1 ]
Durgham, Ryan A. [1 ]
Nguyen, Shaun A. [1 ]
Newman, Jason G. [1 ]
Kejner, Alexandra E. [1 ]
Albergotti, William G. [1 ]
机构
[1] Med Univ South Carolina, Dept Otolaryngol Head & Neck Surg, Charleston, SC 29425 USA
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2025年 / 47卷 / 08期
关键词
cancer-related suicide; head and neck cancer; laryngeal cancer; oropharyngeal cancer; suicide risk factors; QUALITY-OF-LIFE; DEPRESSIVE SYMPTOMS; HUMAN-PAPILLOMAVIRUS; EPIDEMIOLOGY; IDEATION; PREVALENCE; BIAS;
D O I
10.1002/hed.28145
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
BackgroundHead and neck cancer (HNC) patients have an elevated suicide risk. This study examines suicide risk factors among HNC patients. MethodsDatabases were reviewed through June 2024 for articles examining HNC patient suicide. HNC patients, non-HNC cancer patients, and suicide case numbers were stratified by patient variables. Meta-analyses of proportions and relative risk (RR) were performed. ResultsTwenty-one studies with 1 610 031 HNC and 16 857 218 non-HNC cancer patients were included. HNC patients had a higher suicide risk than non-HNC cancer (RR 2.369) and general population (RR 26.991) cohorts. Non-Hispanic ethnicity (RR 3.773), male sex (RR 2.721), and oropharyngeal (RR 1.241) or laryngeal (RR 1.182) cancers increased risk. Being Black (RR 0.316), Hispanic (RR 0.265), and female (RR 0.367) decreased risk. Excluding studies only examining laryngeal cancer intensified sex and race effects on suicide risk. ConclusionsHNC patients have a higher suicide risk than other cancer patients. Laryngeal cancer attenuates the effects of other variables.
引用
收藏
页码:2231 / 2247
页数:17
相关论文
共 51 条
[1]   Global prevalence of suicide by latitude: A systematic review and meta-analysis? [J].
An, Seongjun ;
Lim, Sungju ;
Kim, Hyun-Woo ;
Kim, Hyung-Sik ;
Lee, Dongjun ;
Son, Eunjeong ;
Kim, Tae Woo ;
Goh, Tae Sik ;
Kim, Kihun ;
Him, Yun Hak .
ASIAN JOURNAL OF PSYCHIATRY, 2023, 81
[2]   A Literature Review of Suicide in Cancer Patients [J].
Anguiano, Linda ;
Mayer, Deborah K. ;
Piven, Mary Lynn ;
Rosenstein, Donald .
CANCER NURSING, 2012, 35 (04) :E14-E26
[3]   Long-term functional outcome after laryngeal cancer treatment [J].
Anschuetz, Lukas ;
Shelan, Mohamed ;
Dematte, Marco ;
Schubert, Adrian D. ;
Giger, Roland ;
Elicin, Olgun .
RADIATION ONCOLOGY, 2019, 14 (1)
[4]   Suicide attempts, plans, and ideation in culturally diverse sites:: the WHOSUPRE-MISS community survey [J].
Bertolote, JM ;
Fleischmann, A ;
De Leo, D ;
Bolhari, J ;
Botega, N ;
De Silva, D ;
Thanh, HTT ;
Phillips, M ;
Schlebusch, L ;
Värnik, A ;
Vijayakumar, L ;
Wasserman, D .
PSYCHOLOGICAL MEDICINE, 2005, 35 (10) :1457-1465
[5]   Association of Human Papillomavirus Status With Suicide Risk Among Patients With Head and Neck Cancer [J].
Chakoma, Tatenda ;
Moon, Peter K. ;
Osazuwa-Peters, Oyomoare L. ;
Megwalu, Uchechukwu C. ;
Osazuwa-Peters, Nosayaba .
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2023, 149 (04) :291-299
[6]   The Relationship Between Depressive Symptoms and Initial Quality of Life and Function in Head and Neck Cancer [J].
Chan, Jason Y. K. ;
Lua, Lannah L. ;
Starmer, Heather H. ;
Sun, Daniel Q. ;
Rosenblatt, Elizabeth S. ;
Gourin, Christine G. .
LARYNGOSCOPE, 2011, 121 (06) :1212-1218
[7]   Factors associated with suicidal ideation risk in head and neck cancer: A longitudinal study [J].
Chang, Dun-Cheng ;
Chen, Andy Wei-Ge ;
Lo, Yu-Sheng ;
Chuang, Yi-Ching ;
Chen, Mu-Kuan .
LARYNGOSCOPE, 2019, 129 (11) :2491-2495
[8]   Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States [J].
Chaturvedi, Anil K. ;
Engels, Eric A. ;
Pfeiffer, Ruth M. ;
Hernandez, Brenda Y. ;
Xiao, Weihong ;
Kim, Esther ;
Jiang, Bo ;
Goodman, Marc T. ;
Sibug-Saber, Maria ;
Cozen, Wendy ;
Liu, Lihua ;
Lynch, Charles F. ;
Wentzensen, Nicolas ;
Jordan, Richard C. ;
Altekruse, Sean ;
Anderson, William F. ;
Rosenberg, Philip S. ;
Gillison, Maura L. .
JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (32) :4294-4301
[9]   HPV status in unknown primary head and neck cancer: Prognosis and treatment outcomes [J].
Cheraghlou, Shayan ;
Torabi, Sina J. ;
Husain, Zain A. ;
Otremba, Michael D. ;
Osborn, Heather A. ;
Mehra, Saral ;
Yarbrough, Wendell G. ;
Burtness, Barbara A. ;
Judson, Benjamin L. .
LARYNGOSCOPE, 2019, 129 (03) :684-691
[10]   Mental Disorders and Suicide Risk among Cancer Patients: A Nationwide Cohort Study [J].
Choi, Jae Woo ;
Park, Eun-Cheol ;
Kim, Tae Hyun ;
Han, Euna .
ARCHIVES OF SUICIDE RESEARCH, 2022, 26 (01) :44-55