A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by United Kingdom Acute Lymphoblastic Leukemia (UKALL) Chemotherapy Protocol

被引:0
作者
Alzahrani, Musa Fares [1 ,2 ]
机构
[1] King Saud Univ, Coll Med, Dept Med, Riyadh 12372, Saudi Arabia
[2] King Saud Univ Med City, Oncol Ctr, Riyadh 11451, Saudi Arabia
关键词
lymphoblastic lymphoma; UKALL; LBL; B-LBL; epidural; INVOLVEMENT; ADOLESCENTS; CHILDREN; SERIES;
D O I
10.3390/hematolrep16040069
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: B-cell lymphoblastic lymphoma (B-LBL) is an aggressive type of non-Hodgkin lymphoma that usually involves lymph nodes, skin and soft tissue. Bone marrow and peripheral blood are normally spared from involvement in the disease. B-LBL typically forms solid masses that have similar pathologic and immunophenotypic features to their liquid counterpart, B-cell acute lymphoblastic leukemia (B-ALL). The presentation of B-LBL with a solitary epidural mass at the cervical spine is very rare and the optimal treatment of such cases is unknown. Most of the literature on the management of B-LBL comes from small case series, pediatric patients, or as part of retrospective data that combine B-LBL with B-ALL cases. Case presentation: The case presented herein is a unique presentation that was treated using three modalities, namely surgical resection, radiotherapy and consolidation with systemic chemotherapy, adopted from the United Kingdom acute lymphoblastic leukemia (UKALL14) protocol. Conclusions: The patient attained complete remission following the planned treatment and is still in remission for more than four and half years from the time of his initial diagnosis.
引用
收藏
页码:724 / 731
页数:8
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