Exercise Mediates Noncoding RNAs in Cardiovascular Diseases: Pathophysiological Roles and Clinical Application

被引：1

作者：

Wu, Changyong ^{[1
]}

Chen, Xiaocui ^{[2
]}

Yang, Lu ^{[1
]}

Sun, Huang ^{[1
]}

Bao, Suli ^{[1
]}

Li, Haojie ^{[1
]}

Zheng, Lihui ^{[1
]}

Zeng, Huiling ^{[1
]}

Li, Ruijie ^{[1
]}

Peng, Yunzhu ^{[1
]}

机构：

[1] Kunming Med Univ, Dept Cardiol, Affiliated Hosp 1, Kunming, Yunnan, Peoples R China

[2] Panzhihua Univ, Dept Gastroenterol, Affiliated Hosp, Panzhihua, Sichuan, Peoples R China

来源：

EXPERT REVIEWS IN MOLECULAR MEDICINE | 2024年 / 27卷

关键词：

cardiovascular disease; cardiac fibrosis; cardiac rehabilitation; exercise; molecular mechanism; noncoding RNA; INDUCED CARDIAC GROWTH; PHYSICAL-ACTIVITY; HEART-FAILURE; INFLAMMATION; HYPERTROPHY; ASSOCIATION; ADAPTATIONS; GUIDELINES; MORTALITY; PROTECTS;

D O I：

10.1017/erm.2024.25

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Exercise-based cardiac rehabilitation is effective in improving cardiovascular disease risk factor management, cardiopulmonary function, and quality of life. However, the precise mechanisms underlying exercise-induced cardioprotection remain elusive. Recent studies have shed light on the beneficial functions of noncoding RNAs in either exercise or illness models, but only a limited number of noncoding RNAs have been studied in both contexts. Hence, the present study aimed to elucidate the pathophysiological implications and molecular mechanisms underlying the association among exercise, noncoding RNAs, and cardiovascular diseases. Additionally, the present study analysed the most effective and personalized exercise prescription, serving as a valuable reference for guiding the clinical implementation of cardiac rehabilitation in patients with cardiovascular diseases.

引用

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