Toxicity and efficacy of antibody drug conjugates (ADC) in advanced solid tumors: A pooled analysis of Sarah Cannon UK

被引:0
|
作者
Woodford, R. [1 ]
Beygozlu, N. [2 ]
Cammarota, A. [3 ]
Joshi, K. [4 ]
Grochot, R. M. [5 ]
Williams, A. [6 ]
Fontana, E. [5 ]
机构
[1] Sarah Cannon Res Inst SCRI UK, Med Oncol Dept, London, England
[2] UCL, Sci & Technol, London, England
[3] Humanitas Univ, Med Oncol Dept, Milan, Italy
[4] Sarah Cannon Res Inst SCRI UK, London, England
[5] Sarah Cannon Res Inst SCRI UK, Drug Dev Unit, London, England
[6] Sarah Cannon Res Inst SCRI UK, Med Oncol, London, England
关键词
D O I
10.1016/j.annonc.2024.08.721
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
655P
引用
收藏
页码:S517 / S518
页数:2
相关论文
共 50 条
  • [21] Treatment of solid tumors with antibody drug conjugates targeting aberrant O-glycoproteins
    Groen, Aaron C.
    Shrestha, Nisha
    Klebanov, Boris
    Yu, Byeongjun
    Lee, BeomYong
    Chung, Chul-Woong
    Park, Changsik
    Aasted, Mikkel K.
    Dabelsteen, Sally
    Wandall, Hans H.
    CANCER RESEARCH, 2024, 84 (06)
  • [22] Antibody-Drug Conjugates for the Treatment of Solid Tumors: Clinical Experience and Latest Developments
    Nagayama, Aiko
    Ellisen, Leif W.
    Chabner, Bruce
    Bardia, Aditya
    TARGETED ONCOLOGY, 2017, 12 (06) : 719 - 739
  • [23] Optimizing peptide-drug conjugate delivery as an alternative to antibody-drug conjugates for solid tumors
    Sottero, Theo L.
    Girard, Emily J.
    Myers, Carrie H.
    Olson, James M.
    CANCER RESEARCH, 2017, 77
  • [24] STOPIN: A new approach to solve the hematological toxicity of antibody-drug conjugates (ADC) with soft topoisomerase inhibitor
    Wang, X.
    Yang, H.
    Li, Y.
    Wang, L.
    Liu, S.
    ANNALS OF ONCOLOGY, 2024, 35 : S227 - S227
  • [25] Efficacy and toxicity of antibody-drug conjugates in the treatment of metastatic urothelial cancer: A scoping review
    de Padua, Tiago Costa
    Moschini, Marco
    Martini, Alberto
    Pederzoli, Filippo
    Nocera, Luigi
    Marandino, Laura
    Raggi, Daniele
    Briganti, Alberto
    Montorsi, Francesco
    Necchi, Andrea
    UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2022, 40 (10) : 413 - 423
  • [26] Efficacy and toxicity of KRASG12C inhibitors in advanced solid tumors: a meta-analysis
    Dang, Shoutao
    Zhang, Shuyang
    Zhao, Jingyang
    Li, Wei
    WORLD JOURNAL OF SURGICAL ONCOLOGY, 2024, 22 (01)
  • [27] A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects
    Burton, Jackson K.
    Bottino, Dean
    Secomb, Timothy W.
    AAPS JOURNAL, 2019, 22 (01):
  • [28] Combining antibody-drug conjugates with immunotherapy in solid tumors: current landscape and future perspectives
    Nicolo, Eleonora
    Giugliano, Federica
    Ascione, Liliana
    Tarantino, Paolo
    Corti, Chiara
    Tolaney, Sara M.
    Cristofanilli, Massimo
    Curigliano, Giuseppe
    CANCER TREATMENT REVIEWS, 2022, 106
  • [29] A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects
    Jackson K. Burton
    Dean Bottino
    Timothy W. Secomb
    The AAPS Journal, 22
  • [30] Therapeutic efficacy of antibody-drug conjugates targeting GD2-positive tumors
    Kalinovsky, Daniel, V
    Kibardin, Alexey, V
    Kholodenko, Irina, V
    Svirshchevskaya, Elena, V
    Doronin, Igor I.
    Konovalova, Mariya, V
    Grechikhina, Maria, V
    Rozov, Fedor N.
    Larin, Sergey S.
    Deyev, Sergey M.
    Kholodenko, Roman, V
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (06)