The Current Status of Adjuvant Chemotherapy for Colorectal Cancer in Japan: A Paradigm Shift from Oral Fluoropyridine Single Therapy to the Oxaliplatin Regimen

被引：0
|
作者：
Teranishi, Nobuhisa [1 ]
Uetake, Hiroyuki [1 ]
机构：
[1] Natl Hosp Org NHO, Disaster Med Ctr, Dept Clin Res, 3256 Midori Cho, Tachikawa 1900014, Japan
来源：
CANCERS | 2025年 / 17卷 / 03期
关键词：
colorectal cancer; adjuvant therapy in Japan; L-OHP; 5-FU + leucovorin; ACHIEVE trial; III COLON-CANCER; STAGE-II; SURVIVAL; FLUOROURACIL; LEUCOVORIN; TRIAL; S-1;
D O I：
10.3390/cancers17030518
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The effectiveness of oxaliplatin (L-OHP) has been reported overseas; however, in Japan, the prognosis of colorectal cancer (CRC) patients is reported to be good, and there has been a long debate about the applicability of L-OHP combination therapy in Japan. In recent years, the results of the ACHIEVE trial have become clear, and the standard consensus in Japan establishes L-OHP combination therapy for a duration of 3 months as the adjuvant treatment for CRC.
引用
收藏
页数：5
相关论文
共 32 条
  • [1] Adjuvant therapy of colorectal cancer From coffee to acetylsalicylic acid to chemotherapy
    Kraeft, A-L
    Reinacher-Schick, A.
    Folprecht, G.
    GASTROENTEROLOGE, 2020, 15 (04): : 290 - 299
  • [2] Adjuvant chemotherapy for elderly patients with colorectal cancer: a single-centre observational study in Japan
    Okamoto, Kazuaki
    Nozawa, Hiroaki
    Emoto, Shigenobu
    Murono, Koji
    Sasaki, Kazuhito
    Ishihara, Soichiro
    JOURNAL OF CHEMOTHERAPY, 2024, 36 (04) : 319 - 328
  • [3] Gut microbiome associated with chemotherapy-induced diarrhea from the CapeOX regimen as adjuvant chemotherapy in resected stage III colorectal cancer
    Zuo Fei
    Yin Lijuan
    Yang Xi
    Wu Wei
    Zhong Jing
    Da Miao
    Han Shuwen
    GUT PATHOGENS, 2019, 11 (1)
  • [4] Feasibility Study of Oxaliplatin with Oral S-1 or Capecitabine as First-line Therapy for Patients with Metastases from Colorectal Cancer
    Watanabe, Kazuhiro
    Kawahara, Hidejiro
    Enomoto, Hiroya
    Toyama, Yoichi
    Akiba, Tadashi
    Yanaga, Katsuhiko
    ANTICANCER RESEARCH, 2013, 33 (09) : 4029 - 4032
  • [5] Immune checkpoint inhibitor therapy in neoadjuvant and adjuvant treatment for cancer: A paradigm shift in the treatment of resectable gastrointestinal cancer 3)A paradigm shift in the treatment of colorectal cancer
    Oshima, Kotoe
    Yamazaki, Kentaro
    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2023, 28 (11) : 1442 - 1450
  • [6] Immune checkpoint inhibitor therapy in neoadjuvant and adjuvant treatment for cancer: A paradigm shift in the treatment of resectable gastrointestinal cancer 3)A paradigm shift in the treatment of colorectal cancer
    Kotoe Oshima
    Kentaro Yamazaki
    International Journal of Clinical Oncology, 2023, 28 : 1442 - 1450
  • [7] Clinical compliance with an oral uracil/tegafur (UFT) plus leucovorin (LV) regimen as adjuvant chemotherapy in Japanese colorectal cancer patients
    Meguro, Makoto
    Furuhata, Tomohisa
    Okita, Kenji
    Nishidate, Toshihiko
    Ishiyama, Gentaro
    Iwayama, Yuji
    Kimura, Yasutoshi
    Mizuguchi, Toru
    Hirata, Koichi
    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2009, 14 (05) : 402 - 407
  • [8] Prognostic Value of EGFR Expression for Patients With Stage III Colorectal Cancer Receiving Fluoropyrimidine Metronomic Maintenance Therapy After Radical Resection and Adjuvant Oxaliplatin-Based Chemotherapy
    Huang, Ching-Wen
    Ma, Cheng-Jen
    Su, Wei-Chih
    Chen, Yi-Ting
    Tsai, Hsiang-Lin
    Yeh, Yung-Sung
    Chang, Tsung-Kun
    Hsu, Wen-Hung
    Yu, Fang-Jung
    Wang, Jaw-Yuan
    ONCOLOGY RESEARCH, 2020, 28 (7-8) : 701 - 714
  • [9] Oral Chinese Patent Medicine Combined With Oxaliplatin-Based Chemotherapy Regimen for the Treatment of Colorectal Cancer: A Network Meta-Analysis
    Tang, Mo
    He, Bin
    Zhai, Jiawei
    Wang, Lei
    INTEGRATIVE CANCER THERAPIES, 2021, 20
  • [10] Clinical compliance with an oral uracil/tegafur (UFT) plus leucovorin (LV) regimen as adjuvant chemotherapy in Japanese colorectal cancer patients
    Makoto Meguro
    Tomohisa Furuhata
    Kenji Okita
    Toshihiko Nishidate
    Gentaro Ishiyama
    Yuji Iwayama
    Yasutoshi Kimura
    Toru Mizuguchi
    Koichi Hirata
    International Journal of Clinical Oncology, 2009, 14 : 402 - 407
1234