Background/Objectives: In this study, a medical decision support system is presented to assist physicians in epileptic focus detection by correlating MRI and EEG data of temporal lobe epilepsy patients. Methods: By exploiting the asymmetry in the hippocampus in MRI images and using voxel-based morphometry analysis, gray matter reduction in the temporal and limbic lobes is detected, and epileptic focus prediction is realized. In addition, an epileptic focus is also determined by calculating the asymmetry score from EEG channels. Finally, epileptic focus detection was performed by associating MRI and EEG data with a decision tree. Results: The results obtained from the proposed algorithm provide 100% overlap with the physician's finding on the EEG data. Conclusions: MRI and EEG correlation in epileptic focus detection was improved compared with physicians. The proposed algorithm can be used as a medical decision support system for epilepsy diagnosis, treatment, and surgery planning.
机构:
Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Southern TOHOKU Res Inst Neurosci, Cyclotron & Drug Discovery Res Ctr, 7-61-2 Yatsuyamada, Koriyama, Fukushima 9638052, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Beheshti, Iman
Sone, Daichi
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Natl Ctr Neurol & Psychiat, Integrat Brain Imaging Ctr, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, Japan
UCL Inst Neurol, Dept Clin & Expt Epilepsy, Queen Sq, London WC1N 3BG, England
Jikei Univ, Dept Psychiat, Sch Med, Minato Ku, 3-25-8 Nishishimbashi, Tokyo 1058461, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Sone, Daichi
Maikusa, Norihide
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Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Maikusa, Norihide
Kimura, Yukio
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Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Kimura, Yukio
Shigemoto, Yoko
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机构:
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Shigemoto, Yoko
Sato, Noriko
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机构:
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Sato, Noriko
Matsuda, Hiroshi
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机构:
Southern TOHOKU Res Inst Neurosci, Cyclotron & Drug Discovery Res Ctr, 7-61-2 Yatsuyamada, Koriyama, Fukushima 9638052, Japan
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
机构:
Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Southern TOHOKU Res Inst Neurosci, Cyclotron & Drug Discovery Res Ctr, 7-61-2 Yatsuyamada, Koriyama, Fukushima 9638052, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Beheshti, Iman
Sone, Daichi
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Neurol & Psychiat, Integrat Brain Imaging Ctr, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, Japan
UCL Inst Neurol, Dept Clin & Expt Epilepsy, Queen Sq, London WC1N 3BG, England
Jikei Univ, Dept Psychiat, Sch Med, Minato Ku, 3-25-8 Nishishimbashi, Tokyo 1058461, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Sone, Daichi
Maikusa, Norihide
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Maikusa, Norihide
Kimura, Yukio
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Kimura, Yukio
Shigemoto, Yoko
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Shigemoto, Yoko
Sato, Noriko
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada
Sato, Noriko
Matsuda, Hiroshi
论文数: 0引用数: 0
h-index: 0
机构:
Southern TOHOKU Res Inst Neurosci, Cyclotron & Drug Discovery Res Ctr, 7-61-2 Yatsuyamada, Koriyama, Fukushima 9638052, Japan
Natl Ctr Neurol & Psychiat, Dept Radiol, 4-1-1 Ogawahigashi Cho, Kodaira, Tokyo 1878551, JapanUniv Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Human Anat & Cell Sci, Winnipeg, MB, Canada