Self-reported health, persistent symptoms, and daily activities 2 years after hospitalization for COVID-19

被引:0
作者
Alhasan, Roda [1 ]
Rafsten, Lena [1 ,2 ]
Larsson, Alexandra C. [1 ,2 ]
Sunnerhagen, Katharina S. [1 ,2 ,3 ]
Persson, Hanna C. [1 ,2 ]
机构
[1] Univ Gothenburg, Inst Neurosci & Physiol, Sahlgrenska Acad, Dept Clin Neurosci & Rehabil Med, Gothenburg, Sweden
[2] Sahlgrens Univ Hosp, Dept Occupat Therapy & Physiotherapy, Gothenburg, Sweden
[3] Sahlgrens Univ Hosp, Dept Rehabil Med, Gothenburg, Sweden
关键词
COVID-19; post Covid; persistent symptoms; respiratory symptoms; fatigue; shortness of breath; functional status; daily activities; FATIGUE; COPD;
D O I
10.3389/fncel.2024.1460119
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Introduction: Since the onset of the COVID-19 pandemic, 775 million cases have been reported globally. While many individuals recover fully, a significant proportion develop persistent symptoms. Numerous studies have investigated the long-term symptoms of COVID-19; however, the full extent and impact of these symptoms remain inadequately understood. The aim of this study was to investigate the prevalence of self-reported persistent symptoms, focusing on respiratory symptoms and fatigue and the impact on functional status 2 years after hospitalization for COVID-19. Methods: This study is prospective and includes participants from a longitudinal multi-center cohort that follows patients previously hospitalized due to COVID-19 (n = 211). The current study encompasses the 2-year follow-up, using post-hospitalization questionnaire surveys. Analyzed data were collected before discharge and at the 2-year follow-up. Participants were grouped by age, sex and COVID-19 severity and group comparisons where conducted. Logistic regression analysis was used to study functional impairment. Results: Two years after hospital discharge due to COVID-19, 125 participants completed the 2-year follow-up. The mean age of participants was 66 years (SD 12.2), and 68% were male. The majority of participants reported present respiratory symptoms (n = 83, 69%) and fatigue (n = 98, 78%) at the 2-year follow-up. Persistent respiratory symptoms and fatigue impacted functional status substantially (p = <0.001, p = 0.028, respectively). No significant differences were observed among groups depending on age, sex, or severity of COVID-19. Conclusion: For some individuals regardless of age, sex or COVID-19 severity, respiratory symptoms and fatigue may persist for up to 2 years following COVID-19. Hence, having available support from professionals knowledgeable about COVID-19 is imperative. Further research is important to unravel the mechanisms of long-term symptoms following COVID-19 and to develop effective therapeutic and rehabilitative interventions.
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页数:11
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