The world of phage tail-like bacteriocins: State of the art and biotechnological perspectives

被引：0

作者：

Ibarguren, Clara ^{[1
,2
]}

Bleriot, Ines ^{[1
,2
]}

Blasco, Lucia ^{[1
,2
]}

Fernandez-Garcia, Laura ^{[1
,2
]}

Ortiz-Cartagena, Concha ^{[1
,2
]}

Arman, Lucia ^{[1
,2
]}

Barrio-Pujante, Antonio ^{[1
,2
]}

Rodriguez, Olaya Menendez ^{[1
,3
]}

Garcia-Contreras, Rodolfo ^{[4
]}

Wood, Thomas K. ^{[5
]}

Tomas, Maria ^{[1
,2
,6
]}

机构：

[1] Univ A Coruna UDC, Univ Hosp A Coruna CHUAC, Biomed Res Inst A Coruna INIBIC, Microbiol Serv,Multidisciplinary & Translat Microb, La Coruna, Spain

[2] Spanish Soc Infect Dis & Clin Microbiol SEIMC, Study Grp Mech Act Resistance Antimicrobials GEMAR, Madrid, Spain

[3] Hosp Univ Puerta Hierro, Microbiol Serv, Madrid, Spain

[4] Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Mexico City, Mexico

[5] Penn State Univ, Dept Chem Engn, University Pk, PA 16802 USA

[6] MEPRAM, Proyecto Med Precis Resistencias Antimicrobianas, Madrid, Spain

来源：

MICROBIOLOGICAL RESEARCH | 2025年 / 295卷

关键词：

Phage tail-like bacteriocins (PTLBs); Antimicrobial strategies; PTLBs application; Multidrug resistant bacteria (MDR); HIGH-MOLECULAR-WEIGHT; R-TYPE PYOCINS; PSEUDOMONAS-AERUGINOSA; OSMOTIC SHOCK; F-TYPE; TAILOCINS; PARTICLES; GENES; FORCE;

D O I：

10.1016/j.micres.2025.128121

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In the struggle for resources, bacteria have developed different systems of competition, including the type VI secretion system (T6SS) and phage tail-like bacteriocins (PTLBs), that act by killing other bacterial species or strains from the same species. The emergence of antimicrobial resistance (AMR) is an urgent global health problem. In this context, the need to develop new antimicrobial agents has put PTLBs in the spotlight. This review focuses on the most relevant aspects of PTLBs such as their structural features, biology, the technological tools to improve their application, and the most importantly their patents.

引用

页数：9

共 48 条

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