Functions of actin and myosin in the nucleus

被引:1
作者
Matsumoto, Tomoko [1 ]
Inada, Noriko [1 ]
机构
[1] Osaka Metropolitan Univ, Grad Sch Agr, 1-1 Gakuen Cho,Naka Ku, Sakai, Osaka 5998531, Japan
关键词
Actin; DNA repair; DNA replication; Myosin; Nucleus; Transcription; BETA-ACTIN; TRANSCRIPTION; COMPLEX; EXPRESSION; INITIATION; MECHANISM; INTERACTS; REPAIR;
D O I
10.1508/cytologia.89.263
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In the cytoplasm, actin and myosin together play important roles in cell migration, intracellular transport, regulation of cell shape, cell division, and endocytosis. These functions are carried out by myosin as a motor that moves along actin filaments and creates a motive force. Over the past 20 years, studies have revealed that actin and myosin also function in the nucleus and regulate various nuclear events, including transcription, gene positioning, DNA repair, and DNA replication. In this review, we summarize the known nuclear functions of actin and myosin and the associated molecular mechanisms. To date, studies on nuclear actin and myosin have been limited to animal cells. The possibility that the nuclear functions of actin and myosin are conserved in other organisms, particularly in plants, will be discussed.
引用
收藏
页码:263 / 269
页数:7
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