Integrating molecular imprinting and Fe-based MOF peroxide-like nanozyme for highly sensitive and selective detection of diethylstilbestrol

被引:0
|
作者
Li, Changchang [1 ]
Zhi, Yue [1 ]
Zhu, Minnan [1 ]
Yang, Chengyu [2 ]
Tian, Yayang [1 ]
Chen, Tao [3 ]
Zhao, Yuan [3 ]
Gao, Jie [3 ]
Chen, Linfeng [1 ]
机构
[1] Hubei Univ Sci & Technol, Sch Pharm, Xianning 437100, Peoples R China
[2] Seventh Geol Brigade Hubei Geol Bur, Yichang 443100, Peoples R China
[3] Hubei Univ Sci & Technol, Sch Nucl Technol & Chem & Biol, Hubei Key Lab Radiat Chem & Funct Mat, Xianning 437100, Peoples R China
关键词
Nanozymes; Colorimetric reaction; Diethylstilbestrol; Molecular imprinting technique; SEAWATER; ENZYME;
D O I
10.1016/j.microc.2024.112033
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The development of simple, efficient and low-cost methods for rapid on-site monitoring have always been a challenging topic in the field of analysis. Here, we successfully constructed a selective, sensitive and rapid colorimetric sensor for the sensing of diethylstilbestrol (DES) by using molecular imprinting technology to construct specific recognition sites on the surface of Fe-based metal organic frameworks (Fe-MOF) peroxidaselike nanozyme. The surface of obtained sensor (Fe-MOF@MIP) had abundant channels and imprinted cavities that allowed the substrate to enter and responded with Fe-MOF core to drive the chromogenic reaction of 3,3 ',5,5 '-tetramethylbenzidine (TMB). When DES was present, it could specifically enter the cavities and obstruct the channels of substrate into the Fe-MOF core, thereby inhibiting the chromogenic reaction. The experimental results demonstrate that the sensor had excellent selectivity, anti-interference and catalytic stability. In the linear range of 0 - 1.67 mu M, the detection limit is as low as 8.43 nM, which is superior to peer sensors. To better adapt to in-situ analysis, we have further developed a rapid analysis method based on photo colorimetry, which performed well in real sample analysis and recovery test with the results consistent with the gas chromatographmass spectrometer (GC-MS), demonstrating its great potential for rapid on-site monitoring.
引用
收藏
页数:8
相关论文
共 50 条
  • [1] Facile molecular imprinting on magnetic nanozyme surface for highly selective colorimetric detection of tetracycline
    Liu, Bangxiang
    Zhu, Hengjia
    Feng, Rulin
    Wang, Mengzhu
    Hu, Panwang
    Pan, Jianming
    Niu, Xiangheng
    SENSORS AND ACTUATORS B-CHEMICAL, 2022, 370
  • [2] Novel Fe-based metal-organic framework (MOF) modified carbon nanofiber as a highly selective and sensitive electrochemical sensor for tetracycline detection
    Song, Jialing
    Huang, Manhong
    Lin, Xuanhao
    Li, Sam Fong Yau
    Jiang, Nan
    Liu, Yanbiao
    Guo, Huidong
    Li, Yongmei
    CHEMICAL ENGINEERING JOURNAL, 2022, 427
  • [3] Molecular imprinting ratiometric fluorescence sensor for highly selective and sensitive detection of phycocyanin
    Wang, Xiaoyan
    Yu, Jialuo
    Kang, Qi
    Shen, Dazhong
    Li, Jinhua
    Chen, Lingxin
    BIOSENSORS & BIOELECTRONICS, 2016, 77 : 624 - 630
  • [4] A Co-based MOF as nanozyme with enhanced oxidase-like activity for highly sensitive and selective colorimetric differentiation of aminophenol isomers
    Ren, Mengzhen
    Zhang, Yujie
    Yu, Lanlan
    Qu, Lingbo
    Li, Zhaohui
    Zhang, Lin
    TALANTA, 2023, 255
  • [5] Mo-doped carbon-dots nanozyme with peroxide-like activity for sensitive and selective smartphone-assisted colorimetric S2-ion detection and antibacterial application
    Li, Dai
    Chen, Huajie
    Zheng, Yutao
    Zhou, Sheng
    Yong, Fengyuan
    Zhang, Xiangbo
    Wang, Kui
    Wen, Huiyun
    Wu, Jiyong
    Xue, Weiming
    Huang, Saipeng
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 326
  • [6] Development of a Silver-Based MOF Oxidase-Like nanozyme modified with molecularly imprinted polymer for sensitive and selective colorimetric detection of quercetin
    Karrat, Abdelhafid
    Benssbihe, Jihane
    Ameen, Sameera Sh. Mohammad
    Omer, Khalid M.
    Amine, Aziz
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 330
  • [7] Highly selective and sensitive determination of doxycycline integrating enrichment with thermosensitive magnetic molecular imprinting nanomaterial and carbon dots based fluorescence probe
    Li, Zhi
    Li, Shuangying
    Li, Yanhui
    Liu, Menghua
    Jiang, Liushan
    Niu, Jinwen
    Zhang, Yue
    Zhou, Qingxiang
    SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 896
  • [8] Simultaneous phase-inversion and imprinting based sensor for highly sensitive and selective detection of bisphenol A
    Yang, Qian
    Wu, Xiaqing
    Peng, Hailong
    Fu, Longwen
    Song, Xingliang
    Li, Jinhua
    Xiong, Hua
    Chen, Lingxin
    TALANTA, 2018, 176 : 595 - 603
  • [9] Highly sensitive electrochemical detection of melatonin based on graphene-assisted molecular imprinting technology
    Bin Sun
    Wei Sun
    Zhigang Wang
    Bo Zhao
    Song Yang
    Carbon Letters, 2024, 34 : 437 - 444
  • [10] Highly sensitive electrochemical detection of melatonin based on graphene-assisted molecular imprinting technology
    Sun, Bin
    Sun, Wei
    Wang, Zhigang
    Zhao, Bo
    Yang, Song
    CARBON LETTERS, 2024, 34 (01) : 437 - 444