Molecular mechanism and research progress of traditional Chinese medicine in the treatment of prostate cancer

被引：0

作者：

Wang, Hai-Luo ^{[1
]}

Zhang, Ruo-Ran ^{[2
]}

Wang, Hao ^{[1
]}

Xu, Peng ^{[2
]}

Wang, Jing-Kai ^{[2
]}

Chen, Bo ^{[1
]}

Xu, Hao ^{[3
]}

Pan, Deng ^{[3
]}

Ma, Yu-Yang ^{[3
]}

Pang, Kun ^{[1
,4
,5
]}

机构：

[1] Xuzhou Cent Hosp, Xuzhou Clin Sch, Xuzhou Med Coll, Dept Endocrinol, Xuzhou 221009, Jiangsu, Peoples R China

[2] Jiangsu Univ, Grad Sch, Zhenjiang 212013, Peoples R China

[3] Bengbu Med Univ, Bengbu, Anhui, Peoples R China

[4] Peixian Peoples Hosp, Dept Urol, Xuzhou, Jiangsu, Peoples R China

[5] Xuzhou Med Coll, Xuzhou Cent Hosp, Xuzhou Clin Sch, Dept Urol, 199 South Jiefang Rd, Xuzhou, Jiangsu, Peoples R China

来源：

TRADITIONAL MEDICINE RESEARCH | 2025年 / 10卷 / 01期

基金：

中国博士后科学基金;

关键词：

traditional Chinese medicine; prostate cancer; Chinese herbal medicine; physical therapy; NF-KAPPA-B; ANDROGEN RECEPTOR; HOT FLASHES; IN-VITRO; ANTITUMOR-ACTIVITY; WNT/BETA-CATENIN; DOWN-REGULATION; CELLS; CURCUMIN; APOPTOSIS;

D O I：

10.53388/TMR20240514002

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Prostate cancer (PCa) is one of the most common malignant tumors in the male genitourinary system, ranking second in incidence worldwide. Traditional Chinese medicine (TCM), as an important component of complementary and alternative medicine, shows unique advantages in cancer treatment. Chinese herbal medicine is usually composed of multiple ingredients and involves multiple signaling pathways, which showed function of inducing apoptosis of cancer cells, arresting the cell cycle, inhibiting invasion and metastasis, reducing drug resistance, and regulating immune function. Physical therapy is also an important treatment of TCM. Currently, Physical therapy such as acupuncture or Tai Chi and Qigong are gaining increased recognition in the management of PCa, particularly in addressing issues like urinary incontinence and bone metastasis-related pain. This article reviews the TCM treatment and therapy of PCa, in order to provide new research avenues and treatment options for the treatment of PCa with TCM and improve the quality of life of patients.

引用

页码：18 / 18

页数：1

共 107 条

[11] c-Jun NH2-terminal kinase-induced proteasomal degradation of c-FLIPL/S and Bcl2 sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine [J].

Chaudhary, Pankaj ;

Vishwanatha, Jamboor K. .

BIOCHEMICAL PHARMACOLOGY, 2014, 91 (04) :457-473

[12] Acupuncture for postprostatectomy incontinence: a systematic review [J].

Chen, Huan ;

Liu, Yu ;

Wu, Jiani ;

Liang, Fanrong ;

Liu, Zhishun .

BMJ SUPPORTIVE & PALLIATIVE CARE, 2023, 13 (E1) :E10-E19

[13] Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action [J].

Chen, Jin-Fang ;

Wu, Shi-Wei ;

Shi, Zi-Man ;

Hu, Bing .

CHINESE MEDICINE, 2023, 18 (01)

[14] Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines [J].

Chen, S ;

Ruan, Q ;

Bedner, E ;

Deptala, A ;

Wang, X ;

Hsieh, TC ;

Traganos, F ;

Darzynkiewicz, Z .

CELL PROLIFERATION, 2001, 34 (05) :293-304

[15] Qingdai Decoction suppresses prostate cancer growth in lethal-stage prostate cancer models [J].

Chen, Yanhua ;

Zhou, Qianqian ;

Zhang, Hong ;

Xu, Linfan ;

Lu, Lianheng ;

Shu, Bing ;

Zhou, Lihong ;

Yuan, Fuwen .

JOURNAL OF ETHNOPHARMACOLOGY, 2023, 308

[16] Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways [J].

Chen, Yongqiang ;

Zheng, Lu ;

Liu, Junquan ;

Zhou, Zhonghai ;

Cao, Xiliang ;

Lv, Xiaoting ;

Chen, Fuxing .

INTERNATIONAL IMMUNOPHARMACOLOGY, 2014, 21 (02) :447-455

[17]

Chi N, 2014, INT J CLIN EXP MED, V7, P3181

[18] Celastrol Blocks Interleukin-6 Gene Expression via Downregulation of NF-κB in Prostate Carcinoma Cells [J].

Chiang, Kun-Chun ;

Tsui, Ke-Hung ;

Chung, Li-Chuan ;

Yeh, Chun-Nan ;

Chen, Wen-Tsung ;

Chang, Phei-Lang ;

Juang, Horng-Heng .

PLOS ONE, 2014, 9 (03)

[19] Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo [J].

Chiu, S. C. ;

Huang, S. Y. ;

Chen, S. P. ;

Su, C. C. ;

Chiu, T. L. ;

Pang, C. Y. .

PROSTATE CANCER AND PROSTATIC DISEASES, 2013, 16 (04) :315-322

[20] Curcumin interrupts the interaction between the androgen receptor and Wnt/β-catenin signaling pathway in LNCaP prostate cancer cells [J].

Choi, H. Y. ;

Lim, J. E. ;

Hong, J. H. .

PROSTATE CANCER AND PROSTATIC DISEASES, 2010, 13 (04) :343-349

← 1 2 3 4 5 6 7 8 9 10 →