Quality of life trajectories for different dialysis modalities-a nationwide study

被引：0

作者：

Rydell, Helena ^{[1
,2
,3
]}

Caldinelli, Aurora ^{[4
]}

Wrackefeldt, Jenny ^{[1
,2
]}

Kaveryd-Hult, Aline ^{[3
,5
]}

Lindholm, Bengt ^{[1
]}

Qureshi, Abdul Rashid ^{[1
]}

Chesnaye, Nicholas C. ^{[6
,7
]}

Evans, Marie ^{[1
,2
,3
]}

机构：

[1] Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Renal Med, Stockholm, Sweden

[2] Karolinska Univ Hosp, Renal unit, Stockholm, Sweden

[3] Swedish Renal Registry, Jonkoping, Sweden

[4] Karolinska Inst, Dept Med Epidemiol & Biostat MEB, Solna, Sweden

[5] Sahlgrens Univ Hosp, Transplant Ctr, Gothenburg, Sweden

[6] Univ Amsterdam, Amsterdam UMC locat, ERA Registry, Med Informat, Meibergdreef 9, Amsterdam, Netherlands

[7] Amsterdam Publ Hlth Res Inst, Qual Care, Amsterdam, Netherlands

来源：

CLINICAL KIDNEY JOURNAL | 2025年 / 18卷 / 02期

关键词：

home hemodialysis; in-center hemodialysis; peritoneal dialysis; quality of life; RAND-36; PERITONEAL-DIALYSIS; KIDNEY-TRANSPLANTATION; NOCTURNAL HEMODIALYSIS; DISEASE; COMMUNITY; SURVIVAL; OUTCOMES; IMPACT;

D O I：

10.1093/ckj/sfae420

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background Few contemporary studies have investigated the changes in quality of life across dialysis modalities. Our aim was to compare longitudinal changes in health-related physical and mental quality of life between patients on institutional hemodialysis (IHD), peritoneal dialysis (PD) and home hemodialysis (HHD).Methods Patients on dialysis with registered Research and Development 36 (RAND-36) questionnaires between 2017-2021 in the Swedish Renal Registry (SRR) were eligible for inclusion. Information on dialysis, patient characteristics and medication were collected from SRR and other registries. Patients were followed up to 39 months. Changes in physical (PCS) and mental (MCS) component summary scores were analyzed in adjusted linear mixed models and joint models.Results We included 930 patients (IHD 714, PD 128, HHD 88) with a median follow-up of 1.8 years (interquartile range 1.0-2.1). At baseline, the mean unadjusted PCS was lower in IHD (30.7; 95% CI 29.9, 31.4) compared with HHD (35.3; 95% CI 33.0, 37.5) and PD (33.2; 95% CI 31.3, 35.1). PCS declined over time in all modalities, but faster for PD compared with IHD (-1.2; 95% CI -2.1, -0.3 per year) and HHD (-1.5, 95% CI -2.9, -0.04). MCS was similar at baseline. HHD had improving MCS trajectory compared to IHD (-1.5, 95% CI -2.8, 0.2) and PD (-2.3, 95% CI -3.9, 0.7), largely resulting from improvement in role limitations caused by mental health (6.2, 95% CI 0.9, 11.5).Conclusion Insights about the variation in quality-of-life trajectories for different dialysis modalities are important for patients to make informed choices.

引用

页数：9

共 44 条

[1] van Walraven C, Manuel DG, Knoll G., Survival trends in ESRD patients compared with the general population in the United States, Am J Kidney Dis, 63, pp. 491-499, (2014)
[2] Go AS, Chertow GM, Fan D, Et al., Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization, N Engl J Med, 351, pp. 1296-1305, (2004)
[3] Wang Y, Hemmelder MH, Bos WJW, Et al., Mapping health-related quality of life after kidney transplantation by group comparisons: a systematic review, Nephrol Dial Transplant, 36, pp. 2327-2339, (2021)
[4] Swedish Renal Registry Annual Report 2022
[5] Saeed F, Sardar MA, Davison SN, Et al., Patients’ perspectives on dialysis decision-making and end-of-life care, Clin Nephrol, 91, pp. 294-300, (2019)
[6] Harwood L, Clark AM., Understanding pre-dialysis modality decision-making: a meta-synthesis of qualitative studies, Int J Nurs Stud, 50, pp. 109-120, (2013)
[7] Budhram B, Sinclair A, Komenda P, Et al., A comparison of patient-reported outcome measures of quality of life by dialysis modality in the treatment of kidney failure: a systematic review, Can J Kidney Health Dis, 7, (2020)
[8] Boateng EA, East L., The impact of dialysis modality on quality of life: a systematic review, J Renal Care, 37, pp. 190-200, (2011)
[9] Chrifi Alaoui A, Touti W, Al Borgi Y, Et al., Comparison of quality of life in end-stage renal disease patients undergoing hemodialysis and peritoneal dialysis in a Moroccan city, Semin Dial, 35, pp. 50-57, (2022)
[10] Berenguer-Martinez JM, Bernal-Celestino RJ, Leon-Martin AA, Et al., Quality of life and related factors in patients undergoing renal replacement therapy at the Hospital General Universitario de Ciudad Real: cross sectional descriptive observational study, J Clin Med, 12, (2023)

← 1 2 3 4 5 →