Recent Advances in Design, Synthesis, and Biological Activity Studies of 1,3-Selenazoles

被引：2
作者：
Makhaeva, Nataliya A. [1 ]
Amosova, Svetlana V. [1 ]
Filippov, Andrey S. [1 ]
Potapov, Vladimir A. [1 ]
Musalov, Maxim V. [1 ]
机构：
[1] Russian Acad Sci, A E Favorsky Irkutsk Inst Chem, Siberian Branch, 1 Favorsky Str, Irkutsk 664033, Russia
来源：
BIOMOLECULES | 2024年 / 14卷 / 12期
基金：
俄罗斯科学基金会;
关键词：
heterocycles; 1,3-selenazoles; synthesis; biological activity; 1,3-selenazole derivatives; ONE-POT SYNTHESIS; SELENIUM-CONTAINING HETEROCYCLES; PRIMARY SELENOCARBOXYLIC AMIDES; HIGH ANTIFUNGAL ACTIVITY; N; N-UNSUBSTITUTED SELENOUREAS; ANTIMICROBIAL EVALUATION; SELENAZOLE DERIVATIVES; EFFICIENT SYNTHESIS; HYPERVALENT IODINE; ANTIVIRAL ACTIVITY;
D O I：
10.3390/biom14121546
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The review examines recent advances in the design and synthesis of 1,3-selenazole derivatives since 2000. Various synthetic approaches to 1,3-selenazoles and reaction conditions are discussed. The beneficial properties of 1,3-selenazoles, especially their biological activity, are emphasized. Compounds with antitumor, antiviral (HIV-1 and HIV-2), antibacterial, antifungal, antiproliferative, anticonvulsant, and antioxidant activity are highlighted.
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页数：45
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