Systematic review on toxicity outcomes of graphene oxide coated materials

被引:0
作者
Yadav, Pushpa [1 ]
Yadav, Upasana [2 ]
机构
[1] Chandra Dent Coll & Hosp, Dept Gen Pathol & Microbiol, Faizabad Rd, Dharsania, India
[2] Amity Univ, Amity Sch Appl Sci, Dept Environm, Lucknow, India
关键词
Graphene oxide; In vitro; In vivo; Toxicity outcomes; Toxicity; CARBON NANOTUBES; IN-VITRO; INFLAMMATORY RESPONSES; CYTOTOXICITY; GENOTOXICITY; CELLS; BIOCOMPATIBILITY; NANOPLATELETS; NANOMATERIALS; NANOSHEETS;
D O I
10.22038/nmj.2025.75667.1837
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Graphene and its derived forms have surfaced as promising substances for a wide range of technological and biomedical purposes. However, it is crucial to evaluate their safety and potential risks to ensure their safe use. This systematic review examines the present state of knowledge regarding the toxicity of graphene oxide (GO) through in-vivo, in-vitro, and other species studies. The aim of this present research was to study toxicity outcomes of GO-coated materials. The literature search was conducted and most important electronic databases (20 studies) were checked and selected for the present study. The findings underscore the need for cautious consideration of GO's potential risks, especially at high concentrations and prolonged exposures. Continued research efforts are essential to gain a deeper understanding of the underlying mechanisms and to develop appropriate safety guidelines for the utilization of GO in various applications.
引用
收藏
页码:140 / 152
页数:13
相关论文
共 78 条
  • [61] Wang K, Ruan J, Song H, Et al., Biocompatibility of graphene oxide, Nanoscale Res Lett, 6, pp. 8-15, (2011)
  • [62] Singh SK, Singh MK, Nayak MK, Et al., Thrombus inducing property of atomically thin graphene oxide sheets, ACS Nano, 5, pp. 4987-4996, (2011)
  • [63] Wang X, Podila R, Shannahan JH, Et al., Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis, Int J Nanomedicine, 8, pp. 1733-1748, (2013)
  • [64] Duch MC, Budinger GR, Liang YT, Et al., Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung, Nano Lett, 11, 12, pp. 5201-5207, (2011)
  • [65] Yan L, Wang Y, Xu X, Et al., Can graphene oxide cause damage to eyesight?, Chem Res Toxicol, 25, pp. 1265-1270, (2012)
  • [66] Wu Q, Yin L, Li X, Tang M, Zhang T, Wang D., Contributions of altered permeability of intestinal barrier and defecation behavior to toxicity formation from graphene oxide in nematode Caenorhabditis elegans, Nanoscale, 5, 20, pp. 9934-9943, (2013)
  • [67] Zorov DB, Juhaszova M, Sollott SJ., Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release, Physiological reviews, 94, 3, pp. 909-950, (2014)
  • [68] Murphy MP., How mitochondria produce reactive oxygen species, Biochemical journal, 417, 1, pp. 1-3, (2009)
  • [69] Akhavan O, Ghaderi E., Toxicity of graphene and graphene oxide nanowalls against bacteria, ACS Nano, 4, pp. 5731-5736, (2010)
  • [70] Hu W, Peng C, Luo W, Lv M, Li X, Li D, Huang Q, Fan C., Graphene-based antibacterial paper, ACS Nano, 4, pp. 4317-4323, (2010)