Prevalence and factors associated with dementia in Lesotho: A cross-sectional, population-based study

被引:0
作者
Johnson, Natalie E. [1 ,2 ]
Belus, Jennifer M. [1 ,2 ]
Gerber, Felix [1 ,2 ]
Lee, Tristan T. [1 ,2 ]
Ayakaka, Irene [2 ,3 ]
Letsoela, Pearl [4 ]
Molulela, Manthabiseng [3 ]
Chammartin, Frederique [1 ,2 ]
Amstutz, Alain [1 ,2 ,5 ,6 ]
Labhardt, Niklaus D. [1 ,2 ]
机构
[1] Univ Hosp, Dept Clin Res, Div Clin Epidemiol, Basel, Switzerland
[2] Univ Basel, Basel, Switzerland
[3] SolidarMed, Partnerships Hlth, Happy Villa, Maseru, Lesotho
[4] Minist Hlth Lesotho, Maseru, Lesotho
[5] Oslo Univ Hosp, Oslo Ctr Biostat & Epidemiol, Oslo, Norway
[6] Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, England
基金
瑞士国家科学基金会;
关键词
body mass index; dementia; Lesotho; lifestyle; physical activity; VALIDATION; QUESTIONNAIRE; PHQ-9;
D O I
10.1002/alz.14614
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
INTRODUCTION: Limited research has examined dementia prevalence and associated factors in Lesotho. This study investigates dementia prevalence and the associated factors in Lesotho. METHODS: A survey in Lesotho included 1738 participants screened for dementia and potential associated factors with a focus on modifiable factors. Associations were evaluated using logistic regression models. RESULTS: The median age was 66 years, with 54.83% women. The prevalence of dementia was 4.89%. Those with depressive symptoms (adjusted odds ratio [aOR]: 3.97, 95% confidence interval [CI]: 1.39-11.30), age >= 75 (aOR: 2.68, 95% CI: 1.42-5.04), and underweight (aOR 2.30, 95% CI: 1.23-4.29) had increased odds of dementia. Those with moderate (aOR: 0.32, 95% CI: 0.17-0.58) to high (aOR: 0.35, 95% CI: 0.16-0.77) physical activity and obesity (aOR: 0.30, 95% CI: 0.11-0.80) presented lower odds for dementia. DISCUSSION: This study provides a contemporary estimate of dementia prevalence in Lesotho, highlighting an association with modifiable factors.
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页数:10
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