Harnessing nanotechnology for cancer treatment

被引:0
|
作者
Zhu, Jiajun [1 ,2 ]
Lee, Haeju [1 ,2 ]
Huang, Ruotong [1 ,2 ]
Zhou, Jianming [2 ]
Zhang, Jingjun [3 ]
Yang, Xiaoyi [2 ]
Zhou, Wenhan [2 ]
Jiang, Wangqing [1 ]
Chen, Shuying [1 ]
机构
[1] Fudan Univ, Huashan Hosp, Dept Lab Med, Shanghai, Peoples R China
[2] Fudan Univ, Shanghai Med Coll, Shanghai, Peoples R China
[3] Shanghai Jiao Tong Univ, Dept Rehabil Med, Shanghai Peoples Hosp 6, Sch Med, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
nanotechnology; cancer treatment; targeted drug delivery; early detection; cancer diagnostics; therapeutic strategies; MESOPOROUS SILICA NANOPARTICLES; TARGETED DRUG-DELIVERY; QUANTUM DOTS; BIOMEDICAL APPLICATIONS; PHOTODYNAMIC THERAPY; CELLULAR INTERNALIZATION; MAGNETIC NANOPARTICLES; THERANOSTIC LIPOSOMES; PHOTOTHERMAL THERAPY; GOLD NANOPARTICLES;
D O I
10.3389/fbioe.2024.1514890
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nanotechnology has become a groundbreaking innovation force in cancer therapy, offering innovative solutions to the limitations of conventional treatments such as chemotherapy and radiation. By manipulating materials at the nanoscale, researchers have developed nanocarriers capable of targeted drug delivery, improving therapeutic efficacy while reducing systemic toxicity. Nanoparticles like liposomes, dendrimers, and polymeric nanomaterials have shown significant promise in delivering chemotherapeutic agents directly to tumor sites, enhancing drug bioavailability and minimizing damage to healthy tissues. In addition to drug delivery, with the utilization of tools such as quantum dots and nanosensors that enables more precise identification of cancer biomarkers, nanotechnology is also playing a pivotal role in early cancer detection and diagnosis. Furthermore, nanotechnology-based therapeutic strategies, including photothermal therapy, gene therapy and immunotherapy are offering novel ways to combat cancer by selectively targeting tumor cells and enhancing the immune response. Nevertheless, despite these progressions, obstacles still persist, particularly in the clinical translation of these technologies. Issues such as nanoparticle toxicity, biocompatibility, and the complexity of regulatory approval hinder the widespread adoption of nanomedicine in oncology. This review discusses different applications of nanotechnology in cancer therapy, highlighting its potential and the hurdles to its clinical implementation. Future research needs to concentrate on addressing these obstacles to unlock the full potential of nanotechnology in providing personalized, effective, and minimally invasive cancer treatments.
引用
收藏
页数:19
相关论文
共 50 条
  • [41] Nanotechnology as a Promising Method in the Treatment of Skin Cancer
    Adamus-Grabicka, Angelika A.
    Hikisz, Pawel
    Sikora, Joanna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (04)
  • [42] Nanotechnology and Pediatric Cancer: Prevention, Diagnosis and Treatment
    Zare-Zardini, H.
    Amiri, A.
    Shanbedi, M.
    Taheri-Kafrani, A.
    Sadri, Z.
    Ghanizadeh, F.
    Neamatzadeh, H.
    Sheikhpour, R.
    Boroujeni, Keyvani F.
    Dehshiri, Masoumi R.
    Hashemi, A.
    Aminorroaya, M. M.
    Dehgahnzadeh, M. R.
    Shahriari, Sh
    IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2015, 5 (04) : 233 - 248
  • [43] Advances in treatment of liver cancer aided by nanotechnology
    不详
    NANOMEDICINE, 2011, 6 (03) : 417 - 418
  • [44] NANOTECHNOLOGY AND NANOSCALE DEVICES - APPLICATIONS IN THE TREATMENT OF CANCER
    Laxmi, K.
    EVERYMANS SCIENCE, 2010, 45 (05): : 301 - 307
  • [45] Application of nanotechnology in the diagnosis and treatment of bladder cancer
    Yadong Xu
    Cheng Luo
    Jieqiong Wang
    Lingwu Chen
    Junxing Chen
    Tianfeng Chen
    Qinsong Zeng
    Journal of Nanobiotechnology, 19
  • [46] Nanotechnology and Matrix Metalloproteinases in Cancer Diagnosis and Treatment
    Gonzalez-Avila, Georgina
    Sommer, Bettina
    Garcia-Hernandez, A. Armando
    Ramos, Carlos
    Flores-Soto, Edgar
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 9
  • [47] Nanotechnology Based Photodynamic Therapy for Cancer Treatment
    Bashyal, Bindu
    Ahmed, Shahad
    Shrestha, Anchal
    AlSallami, Nada
    Ahmed, Nawzat Sadiq
    Alsadoon, Omar Hisham
    Ali, Shaymaa Ismail
    PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON INNOVATIONS IN COMPUTING RESEARCH (ICR'22), 2022, 1431 : 93 - 101
  • [48] Nanotechnology Utilizing Ferroptosis Inducers in Cancer Treatment
    Farzipour, Soghra
    Zefrei, Fatemeh Jalali
    Bahadorikhalili, Saeed
    Alvandi, Maryam
    Salari, Arsalan
    Shaghaghi, Zahra
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2024, 24 (08) : 571 - 589
  • [49] Application of nanotechnology in the diagnosis and treatment of bladder cancer
    Xu, Yadong
    Luo, Cheng
    Wang, Jieqiong
    Chen, Lingwu
    Chen, Junxing
    Chen, Tianfeng
    Zeng, Qinsong
    JOURNAL OF NANOBIOTECHNOLOGY, 2021, 19 (01)
  • [50] Harnessing actinobacteria potential for cancer prevention and treatment
    Pongen, Yimtar L.
    Thirumurugan, Durairaj
    Ramasubburayan, Ramasamy
    Prakash, Santhiyagu
    MICROBIAL PATHOGENESIS, 2023, 183