Research progress in OX40/OX40L in allergic diseases

被引：0
|
作者：
Song, Rongrong [1 ]
Zhang, Huanlei [1 ]
Liang, Zhuoping [1 ]
机构：
[1] Southwest Med Univ, Affiliated Hosp, Dept Otolaryngol Head & Neck Surg, 25 Taiping St, Luzhou 646000, Sichuan, Peoples R China
来源：
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY | 2024年 / 14卷 / 12期
关键词：
allergic rhinitis; asthma; atopic dermatitis; OX40; OX40L; ATOPIC-DERMATITIS; RHINITIS; QUESTIONS; BLOCKADE;
D O I：
10.1002/alr.23469
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
OX40/OX40L are costimulatory molecules in the tumor necrosis factor superfamily. Numerous studies have shown that OX40/OX40L are involved in immune regulation, especially in the proliferation and differentiation of T cells and the generation of memory T cells, which play important roles in allergic diseases. In recent years, the use of OX40/OX40L as therapeutic targets for treating T-cell-mediated diseases has attracted the interest of scholars. This paper reviews the role of OX40/OX40L in allergic diseases and the progress in clinical treatments targeting this signaling pathway.
引用
收藏
页码：1921 / 1928
页数：8
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