Research progress in OX40/OX40L in allergic diseases

被引：1

作者：

Song, Rongrong ^{[1
]}

Zhang, Huanlei ^{[1
]}

Liang, Zhuoping ^{[1
]}

机构：

[1] Southwest Med Univ, Affiliated Hosp, Dept Otolaryngol Head & Neck Surg, 25 Taiping St, Luzhou 646000, Sichuan, Peoples R China

来源：

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY | 2024年 / 14卷 / 12期

关键词：

allergic rhinitis; asthma; atopic dermatitis; OX40; OX40L; ATOPIC-DERMATITIS; RHINITIS; QUESTIONS; BLOCKADE;

D O I：

10.1002/alr.23469

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

OX40/OX40L are costimulatory molecules in the tumor necrosis factor superfamily. Numerous studies have shown that OX40/OX40L are involved in immune regulation, especially in the proliferation and differentiation of T cells and the generation of memory T cells, which play important roles in allergic diseases. In recent years, the use of OX40/OX40L as therapeutic targets for treating T-cell-mediated diseases has attracted the interest of scholars. This paper reviews the role of OX40/OX40L in allergic diseases and the progress in clinical treatments targeting this signaling pathway.

引用

页码：1921 / 1928

页数：8

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