Applying the Modified Five-Item Frailty Index to Predict Complications following Lower Extremity Free Flap Reconstruction in Trauma Patients

被引：0

作者：

Gonzalez, Miguel ^{[1
]}

Zietowski, Maeson ^{[1
]}

Patel, Ronak ^{[1
]}

Chattha, Anmol ^{[1
]}

Cripps, Courtney N. ^{[1
]}

Beederman, Maureen ^{[1
]}

机构：

[1] Univ Chicago Med, Dept Surg, Sect Plast & Reconstruct Surg, 5841 S Maryland Rm J641 MC 6035, Chicago, IL 60637 USA

来源：

JOURNAL OF RECONSTRUCTIVE MICROSURGERY | 2025年

关键词：

frailty; limb salvage; trauma; free flap; lower extremity; mFI-5; PREOPERATIVE RISK-ASSESSMENT; FREE TISSUE TRANSFER; FRACTURES; OUTCOMES;

D O I：

10.1055/a-2508-6716

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background Free flap reconstruction in the setting of lower extremity trauma continues to be a challenging clinical problem fraught with a high risk of complications including flap compromise. Although studies have described certain risk factors that predispose these patients to poor outcomes, there remains a paucity of literature detailing frailty as a risk factor. As such, the aim of our study was to examine the application of the 5-item modified frailty index (mFI-5) in trauma patients undergoing lower extremity free flap reconstruction. Methods The 2012 to 2020 American College of Surgeons-National Surgical Quality Improvement Program database was queried for lower extremity free flap reconstructive procedures. After excluding nontrauma etiologies, patients were stratified into three cohorts by their respective mFI-5 score (0, 1, and >= 2). Univariate and multivariate logistic regressions were performed to assess the effect of mFI-5 scores on postoperative complications. Results A total of 219 patients were included (64.8% male) with an average age of 47.6 +/- 16 years. A total of 22.4% (n = 49) of patients had at least one complication. An increased mFI-5 score was associated with an increase in any complication (p < 0.001), hematological complication (p = 0.023), and reoperation (p = 0.004) rates. A high mFI-5 score was found to be an isolated risk factor for having at least one complication (mFI-5 >= 2: odds ratio [OR]: 3.829; p < 0.007; 95% confidence interval [CI]: 1.445-10.145) and reoperation (mFI-5 >= 2: OR: 5.385; p < 0.002; 95% CI: 1.826-15.877). Conclusion Our results indicate that the mFI-5 can be a helpful assessment tool for lower extremity trauma patients undergoing free flap reconstruction to predict the risk of surgical complications and reoperation rates. Patients with an mFI-5 score > 2 should be counseled preoperatively of their increased risk of complications.

引用

页数：6