Stochastic modeling of COVID-19 spread in India: an approach incorporating logarithmic mean-reverting Ornstein-Uhlenbeck process with two-dose vaccine impact analysis

被引:0
作者
Midhun, T. A. [1 ]
Jose, Sayooj Aby [2 ]
Murugesan, K. [1 ]
Jirawattanapanit, Anuwat [2 ]
机构
[1] Natl Inst Technol, Dept Math, Tiruchirappalli, Tamil Nadu, India
[2] Phuket Rajabhat Univ, Fac Educ, Dept Math, Phuket, Thailand
关键词
Dual vaccine doses; Extinction; Ornstein-Uhlenbeck process; SARS-CoV-2; Stationary distribution; AGE;
D O I
10.1007/s11071-025-10917-7
中图分类号
TH [机械、仪表工业];
学科分类号
0802 ;
摘要
The COVID-19 pandemic has introduced unparalleled challenges worldwide, highlighting the need for sophisticated models to understand its dynamics. In this study, we present a comprehensive analysis of a stochastic model incorporating dual doses of vaccine and the logarithmic mean-reverting Ornstein-Uhlenbeck process to analyze the dynamics of SARS-CoV-2 (the virus responsible for COVID-19) infection in India. The study begins with constructing a deterministic model and then it is extended to a stochastic framework. Firstly, we perform a thorough analysis of the deterministic model to confirm the existence and uniqueness of a globally positive solution, ensuring that it remains bounded. Additionally, the basic reproduction number R(0)(d)is derived and the local asymptotic stability of the disease-free equilibrium is evaluated under the condition R-0(d)<1. Next, we analyze the formulated stochastic model and identify two critical thresh-old parameters, R-0(e) and R-0(s). Specifically, R-0(e) <1 indicates exponential extinction of the infection, whereas R-0(s)>1 suggests the potential persistence of the infection due to the existence of at least one stationary distribution. Finally, the model is fitted to the actual COVID-19 case data from India during the peak of the second epidemic wave. The insights derived from these projections, particularly regarding the timing of extinction and the magnitude of the infection peak under various scenarios are crucial for public health policymakers for future outbreaks similar to COVID-19.
引用
收藏
页码:15685 / 15723
页数:39
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