Sleep Apnea Detection Using EEG: A Systematic Review of Datasets, Methods, Challenges, and Future Directions

PurposeSleep Apnea (SA) affects an estimated 936 million adults globally, posing a significant public health concern. The gold standard for diagnosing SA, polysomnography, is costly and uncomfortable. Electroencephalogram (EEG)-based SA detection is promising due to its ability to capture distinctive sleep stage-related characteristics across different sub-band frequencies. This study aims to review and analyze research from the past decade on the potential of EEG signals in SA detection and classification focusing on various deep learning and machine learning techniques, including signal decomposition, feature extraction, feature selection, and classification methodologies.MethodA systematic literature review using the preferred reporting items for systematic reviews and meta-Analysis (PRISMA) and PICO guidelines was conducted across 5 databases for publications from January 2010 to December 2024.ResultsThe review involved screening a total of 402 papers, with 63 selected for in-depth analysis to provide valuable insights into the application of EEG signals for SA detection. The findings underscore the potential of EEG-based methods in improving SA diagnosis.ConclusionThis study provides valuable insights, showcasing significant advancements while identifying key areas for further exploration, thereby laying a strong foundation for future research in EEG-based SA detection.