Step-by-Step Towards Biological Homochirality - from Prebiotic Randomness To Perfect Asymmetry

被引：0

作者：

Mejdrova, Ivana ^{[1
]}

Wegrzyn, Ewa ^{[1
]}

Carell, Thomas ^{[1
]}

机构：

[1] Ludwig Maximilians Univ LMU Munchen, Inst Chem Epigenet ICE M, Dept Chem, Butenandtstr 5-13, D-81377 Munich, Germany

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2025年 / 20卷 / 01期

基金：

欧洲研究理事会;

关键词：

Prebiotic chemistry; Origin of life; Abiogenesis; Homochirality; RNA-peptide world; L-AMINO-ACIDS; CHIRAL-SELECTIVE AMINOACYLATION; CIRCULARLY-POLARIZED-LIGHT; ENANTIOMERIC EXCESS; PARITY VIOLATION; RNA; ORIGIN; AMPLIFICATION; ADSORPTION; RIBOSOME;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The history of life's formation and the origin of its stereochemistry are nearly as multifaceted as the life itself. In this review, we focus on analyzing the step-by-step path leading to what we can define as "life" in parallel to what we know about the emergence of enantiomeric imbalance and subsequent transition to full homochirality. We start at the level of assembly of the building blocks of life from inorganic molecules and build up to the polymerization and formation of nucleic acids and peptides. We report and analyze different theories at various stages of this development and try to elucidate the most plausible theory.

引用

页数：11

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