Sex Differences in the Incidence of Sudden Cardiac Arrest/Death in Competitive Athletes: A Systematic Review and Meta-analysis

被引:0
作者
Li, Lingxia [1 ,2 ,3 ]
Lahaye, Solene Le Douairon [3 ,4 ]
Ding, Shuzhe [2 ]
Schnell, Frederic [5 ,6 ,7 ]
机构
[1] East China Normal Univ, Coll Phys Educ & Hlth, Sino French Joint Res Ctr Sport Sci, Shanghai, Peoples R China
[2] East China Normal Univ, Coll Phys Educ & Hlth, Shanghai, Peoples R China
[3] Univ Rennes 2, Movement Sport & Hlth Sci Lab M2S, Rennes, France
[4] Ecole Normale Super Rennes, Rennes, France
[5] Pontchaillou Hosp, Dept Sports Med, Rennes, France
[6] Univ Rennes, LTSI, INSERM, U1099, Rennes, France
[7] Univ Rennes, Univ Hosp, C 1414, INSERM, Rennes, France
关键词
HIGH-SCHOOL; HYPERTROPHIC CARDIOMYOPATHY; UNITED-STATES; DEATH; SPORTS; YOUNG; RISK; EPIDEMIOLOGY; PARTICIPANTS; EXERCISE;
D O I
10.1007/s40279-024-02163-5
中图分类号
G8 [体育];
学科分类号
04 ; 0403 ;
摘要
BackgroundAlthough many studies have demonstrated a lower incidence of sudden cardiac arrest or death (SCA/D) in female athletes than in male, there is limited understanding of the specific underlying causes.ObjectiveThis systematic review aimed to assess the disparities in SCA/D incidence between male and female competitive athletes and explore the associated etiologies.MethodsA comprehensive search was conducted for retrospective and prospective studies examining SCA/D incidence in male and female athletes. Incidence and incidence rate ratios (IRRs) according to sex were evaluated.ResultsAmong the 16 studies analyzed, 1797 cases of SCA/D were observed; 1578 occurred in males (87.81%). Ages ranged from adolescent to adult. The incidence was 1.42/100,000 athlete-years (AY) in males (95% CI 0.97-2.09), and 0.32/100,000 AY in females (95% CI 0.17-0.59), resulting in an IRR of 5.55. When considering athletes aged <= 35 years, the incidence was 1.46/100,000 AY in males (95% CI 0.91-2.34) and 0.30/100,000 AY in females (95% CI 0.14-0.66), with an IRR of 5.47. The IRR was 5.13 (95% CI 3.94-6.67) for the most recent studies with athletes enrolled only after the year 2000, versus 6.02 (95% CI 4.59-7.90) for the remaining studies covering all observed years. Hypertrophic cardiomyopathy (HCM) was the predominant cause among males (45.12%), while congenital coronary anomalies were more prevalent in females (33.04%).ConclusionThe incidence of SCA/D in females was approximately 6 times lower than in males, with sex differences also in the leading causes of SCA/D. Understanding these discrepancies could lead to targeted strategies for the prevention of SCD in athletes.Registration number(PROSPERO 2023 CRD42023432022)/05.07.2023.
引用
收藏
页码:697 / 712
页数:16
相关论文
共 63 条
  • [1] Sex Differences in Ischemic Heart Disease Advances, Obstacles, and Next Steps
    Aggarwal, Niti R.
    Patel, Hena N.
    Mehta, Laxmi S.
    Sanghani, Rupa M.
    Lundberg, Gina P.
    Lewis, Sandra J.
    Mendelson, Marla A.
    Wood, Malissa J.
    Volgman, Annabelle S.
    Mieres, Jennifer H.
    [J]. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 2018, 11 (02):
  • [2] Sports-related sudden cardiadc deaths in the young population of Switzerlan
    Asatryan, Babken
    Vital, Cristina
    Kellerhals, Christoph
    Medeiros-Domingo, Argelia
    Grani, Christoph
    Trachsel, Lukas D.
    Schmied, Christian M.
    Saguner, Ardan M.
    Eser, Prisca
    Herzig, David
    Bolliger, Stephan
    Michaud, Katarzyna
    Wilhelm, Matthias
    [J]. PLOS ONE, 2017, 12 (03):
  • [3] Sudden Cardiac Arrest During Sports in Children and Adolescents
    Bohm, Philipp
    Barra, Sergio
    Weizman, Orianne
    Narayanan, Kumar
    Meyer, Tim
    Schmied, Christian
    Bougouin, Wulfran
    Jouven, Xavier
    Marijon, Eloi
    [J]. CIRCULATION, 2024, 149 (10) : 794 - 796
  • [4] Sports-related sudden cardiac arrest in young adults
    Bohm, Philipp
    Meyer, Tim
    Narayanan, Kumar
    Schindler, Matthias
    Weizman, Orianne
    Beganton, Frankie
    Schmied, Christian
    Bougouin, Wulfran
    Barra, Sergio
    Dumas, Florence
    Varenne, Olivier
    Cariou, Alain
    Karam, Nicole
    Jouven, Xavier
    Marijon, Eloi
    [J]. EUROPACE, 2023, 25 (02): : 627 - 633
  • [5] Sports-Related Sudden Cardiac Arrest in Germany
    Bohm, Philipp
    Scharhag, Juergen
    Egger, Florian
    Tischer, Karl-Heinz
    Niederseer, David
    Schmied, Christian
    Meyer, Tim
    [J]. CANADIAN JOURNAL OF CARDIOLOGY, 2021, 37 (01) : 105 - 112
  • [6] Sex differences in coronary heart disease and stroke mortality: a global assessment of the effect of ageing between 1980 and 2010
    Bots, Sophie H.
    Peters, Sanne A. E.
    Woodward, Mark
    [J]. BMJ GLOBAL HEALTH, 2017, 2 (02):
  • [7] Does sports activity enhance the risk of sudden death in adolescents and young adults?
    Corrado, D
    Basso, C
    Rizzoli, G
    Schiavon, M
    Thiene, G
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 42 (11) : 1959 - 1963
  • [8] Screening for hypertrophic cardiomyopathy in young athletes
    Corrado, D
    Basso, C
    Schiavon, M
    Thiene, G
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (06) : 364 - 369
  • [9] Trends in sudden cardiovascular death in young competitive athletes after implementation of a preparticipation screening program
    Corrado, Domenico
    Basso, Cristina
    Pavei, Andrea
    Michieli, Pierantonio
    Schiavon, Maurizio
    Thiene, Gaetano
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2006, 296 (13): : 1593 - 1601
  • [10] Incidence of sudden cardiac death in the young: a systematic review
    Couper, Keith
    Putt, Oliver
    Field, Richard
    Poole, Kurtis
    Bradlow, William
    Clarke, Aileen
    Perkins, Gavin D.
    Royle, Pamela
    Yeung, Joyce
    Taylor-Phillips, Sian
    [J]. BMJ OPEN, 2020, 10 (10):