Epicardial adipose tissue: a new link between type 2 diabetes and heart failure-a comprehensive review

被引：0
作者：
Zhang, Si-jia [1 ]
Wang, Si-wei [2 ,3 ]
Liu, Shi-yu [1 ]
Li, Ping [1 ]
Huang, De-lian [1 ]
Zeng, Xi-xi [2 ]
Lan, Tian [2 ,3 ]
Ruan, Ye-ping [1 ,4 ]
Shi, Hai-jiao [5 ]
Zhang, Xin [1 ,4 ]
机构：
[1] Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, 548 Binwen Rd, Hangzhou 310053, Peoples R China
[2] Wenzhou Med Univ, Quzhou Affiliated Hosp, Quzhou Peoples Hosp, Panvascular Dis Res Ctr, Quzhou 324000, Peoples R China
[3] Wenzhou Med Univ, Quzhou Peoples Hosp, Quzhou Affiliated Hosp, Lab Anim Resources Ctr, Quzhou 324000, Peoples R China
[4] Zhejiang Chinese Med Univ, Chinese Med Plant Essential Oil Zhejiang Engn Res, Hangzhou 310053, Peoples R China
[5] Liaoning Univ Tradit Chinese Med, Affiliated Hosp, Dept Cardiol 3, Huludao 116600, Liaoning, Peoples R China
来源：
HEART FAILURE REVIEWS | 2024年
基金：
中国国家自然科学基金;
关键词：
Diabetic cardiomyopathy; Epicardial adipose tissue; Heart failure; Type; 2; diabetes; MYOCARDIAL TRIGLYCERIDE CONTENT; VISCERAL FAT; CARDIOVASCULAR EVENTS; ECTOPIC FAT; CARDIOMYOPATHY; FIBROSIS; RISK; ROSIGLITAZONE; THICKNESS; OBESITY;
D O I：
10.1007/s10741-024-10478-8
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Diabetic cardiomyopathy is a unique cardiomyopathy that is common in diabetic patients, and it is also a diabetic complication for which no effective treatment is currently available. Moreover, relevant studies have revealed that a link exists between type 2 diabetes and heart failure and that abnormal thickening of EAT is inextricably linked to the development of diabetic heart failure. Numerous clinical studies have demonstrated that EAT is implicated in the pathophysiologic process of diabetic myocardial disease. In this overview, we will introduce the physiology, pathophysiology of the disease and potential therapeutic strategies, knowledge gaps, and future directions of the role of epicardial adipose tissue in type 2 diabetes mellitus and heart failure to promote the development of novel therapeutic approaches to improve the prognosis of patients with diabetic cardiomyopathy.
引用
收藏
页码：477 / 491
页数：15
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