Dendritic Cells: Crucial Regulators of Immune Responses on Cancer Cells

Dendritic Cells (DCs) play a pivotal role in the immune system, acting as sentinels that capture, process and present antigens to T cells, thus initiating and regulating immune responses. Activation of DCs stands at the forefront as they work as coordinators of the immune system, spotting and presenting microbe fragments to T cells, thereby commencing Cell-Mediated Immunity (CMI). This review aims to trace the origin of DCs and find out what makes them stand out among other antigen-presenting cells. The research takes us into the DC mechanisms of activation that affect T-cell proliferation, especially in cancer pathologies. Participants are also outlined the possible effects of DC study related to the oncological treatments' development. Briefly, discrimination based on the complex participation of DCs and T cells should pave the way for more potential interventions for improving immunotherapy and other diseases. In summary, dendritic cells are central players in orchestrating immune responses, including those against cancer cells. Understanding their biology and interactions with cancer cells is crucial for developing effective immunotherapies for cancer treatment.