Photon-Driven Dye Induction Pyroptosis: An Emerging Anti-Tumor Immunotherapy Paradigm

被引：0
作者：
Zeng, Shuang [1 ,2 ]
Wang, Jingyun [1 ,2 ]
Kang, Heemin [3 ]
Li, Haidong [1 ,2 ]
Peng, Xiaojun [1 ]
Yoon, Juyoung [4 ]
机构：
[1] Dalian Univ Technol, State Key Lab Fine Chem, Frontiers Sci Ctr Smart Mat Oriented Chem Engn, Dalian, Peoples R China
[2] Dalian Univ Technol, Key Lab Bio Intelligent Mfg, MOE, Sch Bioengn, 2 Linggong Rd, Dalian 116024, Peoples R China
[3] Korea Univ, Dept Mat Sci & Engn, 145 Anam Ro, Seoul 02841, South Korea
[4] Ewha Womans Univ, Dept Chem & Nanoscience, 52 Ewhayeodae Gil, Seoul 03760, South Korea
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2025年 / 64卷 / 02期
基金：
中国国家自然科学基金; 新加坡国家研究基金会;
关键词：
Photon-driven pyroptosis dye; Photoimmunotherapy; Photodynamic therapy; Photothermal therapy; Immunogenic cell death; CELL-DEATH; CANCER; APOPTOSIS; CLEAVAGE; CHEMOTHERAPY; STRATEGIES; CASPASE-3;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Photoimmunotherapy represents a novel and promising modality in anti-tumor immunotherapy, offering new hope in the realm of cancer treatment due to its distinctive mechanism and substantial therapeutic efficacy. This innovative approach synergistically integrates photon technology with immunological principles, utilizing photon energy to activate the body's immune response. Photon-driven pyroptosis, a pivotal element of photoimmunotherapy, has significantly revitalized the advancement of this discipline. To support this critical progress, this minireview offers an exhaustive examination of the organic dyes presently employed for photon-driven pyroptosis, alongside an analysis of the prevailing challenges and opportunities in dye molecule design. It is our aspiration that this minireview will contribute to the acceleration of developments in photon-driven pyroptosis dye and the broader field of photoimmunotherapy.
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页数：19
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