NEW FLAVONOL GLYCOSIDES FROM THE GENUS Dryas

被引：0

作者：

Olennikov, D. N. ^{[1
]}

Kashchenko, N. I. ^{[1
]}

Shishmarev, V. M. ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Gen & Expt Biol, Siberian Branch, 6 Sakhyanovoi St, Ulan Ude 670047, Russia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2025年

关键词：

Dryas octopetala; Dryas oxyodonta; Dryas sumneviczii; 8-methoxykaempferol; sexangularetin; 8-methoxyquercetin; corniculatusin; lipase inhibitors;

D O I：

10.1007/s10600-025-04621-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Studies of three species of Dryas (D. sumneviczii Serg., D. octopetala L., D. oxyodonta Juz., Rosaceae), growing in Baikal District led to the isolation of 19 flavonoids, including seven new flavonol glycosides. UV and NMR spectroscopic and mass spectrometric data characterized the new flavonoids as 8-methoxykaempferol 3-O-alpha-L-arabinopyranoside (dryadoside A, 1), 8-methoxykaempferol 3-O-alpha-Larabinofuranoside (dryadoside B, 2), 8-methoxyquercetin 3-O-alpha-L-arabinopyranoside (dryadoside C, 3), 8-methoxykaempferol 3-O-(6 ''-O-caffeyl)-beta-D-galactopyranoside (dryadoside D, 5), 8-methoxykaempferol 3-O-(2 ''-O-caffeyl)-alpha-L-arabinofuranoside (dryadoside E, 6), 8-methoxyquercetin 3-O-(6 ''-O-caffeyl)-beta-Dgalactopyranoside (dryadoside F, 7), and 8-methoxyquercetin 3-O-(2 ''-O-caffeyl)-alpha-L-arabinofuranoside (dryadoside G, 8). Compounds 5-8 inhibited the activity of human pancreatic lipase.

引用

页码：237 / 242

页数：6

共 21 条

[1]

Agrawal PK., 1989, Carbon-13 NMR of Flavonoids, P564

[2]

[Anonymous], 2004, Flora of Siberia, Rosaceae

[3] The BABAR detector [J].

Aubert, B ;

Bazan, A ;

Boucham, A ;

Boutigny, D ;

De Bonis, I ;

Favier, J ;

Gaillard, JM ;

Jeremie, A ;

Karyotakis, Y ;

Le Flour, T ;

Lees, JP ;

Lieunard, S ;

Petitpas, P ;

Robbe, P ;

Tisserand, V ;

Zachariadou, K ;

Palano, A ;

Chen, GP ;

Chen, JC ;

Qi, ND ;

Rong, G ;

Wang, P ;

Zhu, YS ;

Eigen, G ;

Reinertsen, PL ;

Stugu, B ;

Abbott, B ;

Abrams, GS ;

Amerman, L ;

Borgland, AW ;

Breon, AB ;

Brown, DN ;

Button-Shafer, J ;

Clark, AR ;

Dardin, S ;

Day, C ;

Dow, SF ;

Fan, Q ;

Gaponenko, I ;

Gill, MS ;

Goozen, FR ;

Gowdy, SJ ;

Gritsan, A ;

Groysman, Y ;

Hernikl, C ;

Jacobsen, RG ;

Jared, RC ;

Kadel, RW ;

Kadyk, J ;

Karcher, A .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2002, 479 (01) :1-116

[4]

Azimova S.S., 2013, Natural compounds Flavonoids: plant sources, structure and properties

[5]

Bagrii OK., 1966, Chem. Nat. Compd, V2, P65

[6] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF FLAVONOID GLYCOSIDES FROM DRYAS-OCTOPETALA [J].

DEBERNARDI, M ;

UBERTI, E ;

VIDARI, G ;

SERVETTAZ, O .

JOURNAL OF CHROMATOGRAPHY, 1984, 284 (01) :269-272

[7] EXPERIMENTAL ECOLOGY OF DRYAS-OCTOPETALA ECOTYPES .1. ECOTYPIC DIFFERENTIATION AND LIFE-CYCLE STAGES OF SELECTION [J].

MCGRAW, JB ;

ANTONOVICS, J .

JOURNAL OF ECOLOGY, 1983, 71 (03) :879-897

[8]

NAWWAR MAM, 1989, PHYTOCHEMISTRY, V28, P1755, DOI 10.1016/S0031-9422(00)97839-7

[9]

NIELSEN J G, 1970, Tetrahedron Letters, V11, P803

[10] New Metabolites of Rhodiola rosea. III. Glycosides of Hydroquinone, Tyrosol, and Rosiridol [J].

Olennikov, D. N. ;

Chirikova, N. K. .

CHEMISTRY OF NATURAL COMPOUNDS, 2024, 60 (04) :609-614

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