Epidemiological landscape of tongue cancer in younger patients in a National Cancer Center in Brazil

被引：0

作者：

Souto, Ana Carolina da Silva ^{[1
]}

da Silva, Beatriz Nascimento Monteiro ^{[2
]}

Heimlich, Fernanda Vieira ^{[3
,4
]}

Soares, Otavio Augusto Brioschi ^{[1
]}

Dias, Fernando Luiz ^{[5
]}

Araujo, Luiz Henrique de Lima ^{[2
]}

de Melo, Andreia Cristina ^{[2
]}

Antunes, Heliton Spindola ^{[2
]}

Thuler, Luiz Claudio Santos ^{[2
]}

Goldemberg, Daniel Cohen ^{[2
,6
,7
]}

机构：

[1] Army Cent Hosp, Army Hlth Serv Res Ctr, Rio De Janeiro, Brazil

[2] Natl Canc Inst, Div Clin Res, Technol Dev, Rio De Janeiro, Brazil

[3] Sao Lucas Univ Ctr, Sao Paulo, Brazil

[4] Aparicio Carvalho Integrated Coll, Rio De Janeiro, Brazil

[5] Natl Canc Inst, Head & Neck Surg Serv, Rio De Janeiro, Brazil

[6] UCL, London, England

[7] Natl Canc Inst, Technol Dev, Div Clin Res, COPQ INCA, Rua Andre Cavalcanti 37-5 Andar Anexo Centro, BR-20231050 Rio De Janeiro, Brazil

来源：

SCIENTIFIC REPORTS | 2024年 / 14卷 / 01期

关键词：

Oral cancer; Oral squamous cell carcinoma; Tongue cancer; Young patients; Survival; SQUAMOUS-CELL CARCINOMA; ORAL TONGUE; NECK-CANCER; HEAD; TOBACCO; TRENDS; WOMEN; RISK; AGE;

D O I：

10.1038/s41598-024-83470-9

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This study investigates the changing epidemiological profile of tongue squamous cell carcinoma (SCC) to young patients, highlighting its rising incidence among non-traditional risk groups. A retrospective descriptive study was conducted, covering data from medical records between 2000 and 2012. Patients were categorised into two age groups (<= 40 years; 41-50 years). Sociodemographic and clinicopathological characteristics were evaluated. A total of 108 patients participated, mostly aged 41-50. Alcohol consumption (43.3%) surpassed smoking. Majority (56.7%) aged <= 40 never smoked. Lateral tongue border was most affected, with stages III and IV prevalent. Patients aged <= 40 were mostly eligible for surgery (44%). Survival tied to staging and surgery; age had no significant impact. Young squamous cell carcinoma patients often lacked traditional risk factors like smoking, underwent surgery, and typically had disease-free margins. The study underscores the importance of broad external policies for early diagnosis, beyond just traditional risk groups.

引用

页数：10

共 42 条

[1] Human papillomavirus and head and neck squamous cell carcinoma in a UK population: Is there an association? [J].

Al-Dabbagh, Raghad ;

Al-Hazmi, Nadia ;

Alhazzazi, Turki Y. ;

Barrett, Aw ;

Speight, Paul M. .

INDIAN JOURNAL OF CANCER, 2022, 59 (01) :65-72

[2] Molecular profile of tongue cancer in an 18-year-old female patient with no recognizable risk factor [J].

Ambele, Melvin A. ;

Pepper, Michael S. ;

van Heerden, Marlene B. ;

van Heerden, Willie F. P. .

LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY, 2019, 4 (03) :310-313

[3] Outcome of oral tongue squamous cell carcinoma in patients with and without known risk factors [J].

Bachar, G. ;

Hod, R. ;

Goldstein, D. P. ;

Irish, J. C. ;

Gullane, P. J. ;

Brown, D. ;

Gilbert, R. W. ;

Hadar, T. ;

Feinmesser, R. ;

Shpitzer, T. .

ORAL ONCOLOGY, 2011, 47 (01) :45-50

[4] Genetic Mutations in Young Nonsmoking Patients With Oral Cavity Cancer: A Systematic Review [J].

Bahethi, Rohini R. ;

Stepan, Katelyn O. ;

Pinotti, Rachel ;

Li, Ryan ;

Agrawal, Nishant ;

Puram, Sidharth, V ;

Miles, Brett A. ;

Barber, Brittany .

OTO OPEN, 2020, 4 (04)

[5]

Barsouk A., 2021, Med. Sci, V11, P004, DOI [10.3390/medsci11020004, DOI 10.3390/MEDSCI11020004]

[6] Oral Cavity and Pharynx Cancer Incidence Trends by Subsite in the United States: Changing Gender Patterns [J].

Brown, Linda Morris ;

Check, David P. ;

Devesa, Susan S. .

JOURNAL OF ONCOLOGY, 2012, 2012

[7] HEAD AND NECK-CARCINOMA IN PATIENTS UNDER 40 YEARS OF AGE [J].

CARNIOL, PJ ;

FRIED, MP .

ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1982, 91 (02) :152-155

[8] Oral Squamous Cell Carcinoma Frequency in Young Patients from Referral Centers Around the World [J].

Costa, Rafael Ferreira e ;

Leao, Marina Luiza Baiao ;

Sant'Ana, Maria Sissa Pereira ;

Mesquita, Ricardo Alves ;

Gomez, Ricardo Santiago ;

Santos-Silva, Alan Roger ;

Khurram, Syed Ali ;

Tailor, Artysha ;

Schouwstra, Ciska-Mari ;

Robinson, Liam ;

van Heerden, Willie F. P. ;

Tomasi, Ramiro Alejandro ;

Gorrino, Romina ;

de Prato, Ruth Salome Ferreyra ;

Taylor, Adalberto Mosqueda ;

Urizar, Jose Manuel Aguirre ;

de Mendoza, Irene Lafuente Ibanez ;

Radhakrisnan, Raghu ;

Chandrashekar, Chetana ;

Choi, Siu-Wai ;

Thomson, Peter ;

Pontes, Helder Antonio Rebelo ;

Fonseca, Felipe Paiva .

HEAD & NECK PATHOLOGY, 2022, 16 (03) :755-762

[9] Epidemiology of tongue squamous cell carcinoma: A retrospective cohort study [J].

da Silva Souto, Ana Carolina ;

Vieira Heimlich, Fernanda ;

Lima de Oliveira, Leticia ;

Bergmann, Anke ;

Dias, Fernando Luiz ;

Spindola Antunes, Heliton ;

de Melo, Andreia Cristina ;

Thuler, Luiz Claudio Santos ;

Cohen Goldemberg, Daniel .

ORAL DISEASES, 2023, 29 (02) :402-410

[10] Psychometric properties of the Fagerstrom Test for Nicotine Dependence [J].

de Meneses-Gaya, Izilda Carolina ;

Zuardi, Antonio Waldo ;

Loureiro, Sonia Regina ;

de Souza Crippa, Jose Alexandre .

JORNAL BRASILEIRO DE PNEUMOLOGIA, 2009, 35 (01) :73-82

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