As climate change affects the physicochemical properties of coastal water, the resulting element re-exposure may override the emission reductions achieved by human pollution control efforts. Here, we conduct an analysis the water quality-climate effect over eight consecutive years from 2015 to 2022 along the South China coast combined with CMIP6 Scenario Model Intercomparison Project. Then we utilized a data-driven model to predict the concentrations of trace metals and nutrients over the next 80 years. It is suggested that the acidification process carries the risk of triggering the ocean's buffering mechanisms. During this alkalinity replenishment process, trace metals, such as Cd, Cr, Cu, Fe, Hg, Mn, Pb, and Zn, in the sediment are released into the water phase, along with Ca2+ and Mg2+. Here, the aim of this study is to show that the nexus of re-exposure-eutrophication-emission reduction with human activities and climate feedback, cannot be ignored in the pursuit of effective environmental governance.