Evaluating the 1-year success and safety of ab interno canaloplasty in combination with cataract surgery in glaucoma patients

Purpose To evaluate the treatment success and safety of ab interno canaloplasty (AbiC) combined with cataract surgery in glaucoma patients. Methods The prospective case study included 43 eyes that received an AbiC combined with cataract surgery (age 73.3 +/- 8.2 years). The 360 degrees microcatheterization and viscodilatation of the Schlemm's canal was conducted using VISCO 360 (Sight Sciences, CA, USA). The observation period was 12 months with visits at 2 and 6 as well as 12 months, 7 eyes were lost to follow up. Results The preoperative IOP was 19.8 +/- 4.9 mmHg and was reduced to 14.5 +/- 2.8 mmHg 12 months after AbiC (p < 0.0001). The relative IOP reduction was 23.6 +/- 23.1% after 12 months. Topical glaucoma medication was also reduced from 2.4 +/- 1.1 drugs to 1.1 +/- 1.4 (p < 0.001) after 12 months. The complete surgical success rate (defined as IOP < 18 mmHg without topical therapy) was 31.6% whereas the qualified surgical success was 89.5% (IOP < 18 mmHg, with local therapy) There were no relevant intra- or postoperative complications. Conclusion AbiC in combination with cataract surgery is a safe and effective procedure to achieve a significant reduction of IOP and local glaucoma medication 12 months after surgery.