Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks

被引:0
|
作者
Rastogi, Deependra [1 ]
Johri, Prashant [2 ]
Donelli, Massimo [3 ,4 ]
Kadry, Seifedine [5 ,6 ]
Khan, Arfat Ahmad [7 ]
Espa, Giuseppe [4 ]
Feraco, Paola [8 ]
Kim, Jungeun [9 ]
机构
[1] IILM Univ, Sch Comp Sci & Engn, Noida 201306, UP, India
[2] Galgotias Univ, SCSE, Noida 203201, UP, India
[3] Univ Trento, Dept Civil Environm Mech Engn, I-38100 Trento, Italy
[4] Univ Trento, Dept Econ & Management, Radi Lab, I-38100 Trento, Italy
[5] Lebanese Amer Univ, Dept Comp Sci & Math, Beirut, Lebanon
[6] Noroff Univ Coll, N-4612 Kristiansand, Norway
[7] Simpson Univ, Dept Engn, Redding, CA 96003 USA
[8] Santa Chiara Hosp, Azienda Prov & Serv sanitari, Neuroradiol Unit, I-38100 Trento, Italy
[9] Inha Univ, Dept Comp Engn, Incheon, South Korea
来源
SCIENTIFIC REPORTS | 2025年 / 15卷 / 01期
关键词
Brain tumor; Magnetic resonance imaging; Feature extraction; Segmentation; Survival days prediction; Deep learning; 3D replicator neural network; 2D volumetric Convolutional Network; TEXTURE FEATURES; NEURAL-NETWORK; CLASSIFICATION; IMAGES;
D O I
10.1038/s41598-024-84386-0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of the patients' overall survival rate. Therefore, we have introduced a deep learning approach that employs a combination of MRI scans to accurately segment brain tumors and predict survival in patients with gliomas. To ensure strong and reliable tumor segmentation, we employ 2D volumetric convolution neural network architectures that utilize a majority rule. This method helps to significantly decrease model bias and improve performance. Additionally, in order to predict survival rates, we extract radiomic features from the tumor regions that have been segmented, and then use a Deep Learning Inspired 3D replicator neural network to identify the most effective features. The model presented in this study was successful in segmenting brain tumors and predicting the outcome of enhancing tumor and real enhancing tumor. The model was evaluated using the BRATS2020 benchmarks dataset, and the obtained results are quite satisfactory and promising.
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页数:27
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