Effect of ozone and low power laser as therapeutic alternatives on the alveolar repair process after tooth extraction in rats wistar exposed to nicotine

被引:0
作者
Carvalho, Thainy Oliveira [1 ]
de Almeida, Wilson Pereira [1 ]
Palma, Fabiano Rodrigues [2 ]
Pilati, Paulo Vinicius Fontanella [3 ]
Zanardo, Victoria [1 ]
Chaves, Anna Julia Leduc [1 ]
Pilati, Sarah Freygang Mendes [1 ]
机构
[1] Univ Vale Itajai UNIVALI, R Uruguai 458 Ctr,C5 Ctr, BR-88302901 Itajai, SC, Brazil
[2] Univ Vale Itajai UNIVALI, Anaesthesiol & Surg, R Uruguai 458,C5 Ctr, BR-88302901 Itajai, SC, Brazil
[3] R 119 A,147 Ctr, BR-88220000 Itapema, SC, Brazil
来源
ORAL AND MAXILLOFACIAL SURGERY-HEIDELBERG | 2025年 / 29卷 / 01期
关键词
Nicotine; Alveolar bone repair; Ozone therapy; Laser therapy; PROLIFERATION;
D O I
10.1007/s10006-025-01339-1
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
PurposeThe aim of this study was to evaluate the alveolar repair process in rats exposed to nicotine after tooth extraction, using ozonised water and low-power laser therapy (LPLT) as therapeutic adjuvants.Materials and methodsThirty wistar rats (Rattus Norvegicus) were used and given the nicotine solution via subcutaneous tissue. After 7 days, the upper right central incisor was surgically extracted. Three days after the surgical procedure, the animals continued to receive nicotine until the day of euthanasia, totalling 21 days after extraction.ResultsThe result was that the groups that received coadjuvant therapy had neoformed mature bone, unlike the group that did not receive it.ConclusionsBased on the literature and the results obtained, we can conclude that nicotine negatively influenced the healing process and bone repair in the alveoli; however, the use of ozonised water and LPLT, even in the presence of nicotine, was effective, as it enhanced the repair process, making them good options for surgical procedures in patients who smoke.
引用
收藏
页数:7
相关论文
共 31 条
  • [11] Concise Reviews: Characteristics and Potential Applications of Human Dental Tissue-Derived Mesenchymal Stem Cells
    Liu, Junjun
    Yu, Fang
    Sun, Yao
    Jiang, Beizhan
    Zhang, Wenjun
    Yang, Jianhua
    Xu, Guo-Tong
    Liang, Aibin
    Liu, Shangfeng
    [J]. STEM CELLS, 2015, 33 (03) : 627 - 638
  • [12] Macedo Rander Moreira, 2015, Braz. Dent. J., V26, P175
  • [13] Medeiros Aldo da Cunha, 2003, Acta Cir. Bras., V18, P24
  • [14] Melo A, 2007, dissertation, P116, DOI [10.11606/D.42.2007.tde-03012008-151813, DOI 10.11606/D.42.2007.TDE-03012008-151813]
  • [15] Ozone- A Biological Therapy in Dentistry- Reality or Myth?????
    Naik, Saraswathi V.
    Rajeshwari, K.
    Kohli, Shivani
    Zohabhasan, Sayyad
    Bhatia, Shekhar
    [J]. OPEN DENTISTRY JOURNAL, 2016, 10 : 196 - 206
  • [16] National Research Council of the National Academies, 2011, The guide for the care and use of laboratory animals, V8th ed, DOI DOI 10.17226/12910
  • [17] Cigarette smoking hinders human periodontal ligament-derived stem cell proliferation, migration and differentiation potentials
    Ng, Tsz Kin
    Huang, Li
    Cao, Di
    Yip, Yolanda Wong-Ying
    Tsang, Wai Ming
    Yam, Gary Hin-Fai
    Pang, Chi Pui
    Cheung, Herman S.
    [J]. SCIENTIFIC REPORTS, 2015, 5
  • [18] Meloxicam Temporally Inhibits the Expression of Vascular Endothelial Growth Factor Receptor (VEGFR)-1 and VEGFR-2 During Alveolar Bone Repair in Rats
    Nunes Arantes, Ricardo Vinicius
    Cestari, Tania Mary
    Viscelli, Bruno Alvares
    Dionisio, Thiago Jose
    Garlet, Gustavo Pompermaier
    Santos, Carlos Ferreira
    de Assis, Gerson Francisco
    Taga, Rumio
    [J]. JOURNAL OF PERIODONTOLOGY, 2015, 86 (01) : 162 - 172
  • [19] Office of the Institutional Animal Care and Use Committee (IACUC), 2020, Euthanasia (Guideline)
  • [20] Office of the Institutional Animal Care and Use Committee (IACUC), 2020, Anesthesia (Guideline)