Microwave-Assisted Efficient and Green Synthesis of Dihydropyrimidinone(thione) Derivatives via Biginelli Reaction Using Cashew Shell Extract as Natural Acid Catalyst

被引：0

作者：

Manjare, S. B. ^{[1
]}

Thorat, R. G. ^{[1
]}

Dalvi, S. S. ^{[2
]}

Manval, K. S. ^{[2
]}

More, P. P. ^{[2
]}

Mahadik, R. K. ^{[2
]}

机构：

[1] Univ Mumbai, Dept Chem, Vidyanagari, St acruz E, Mumbai 400098, Maharashtra, India

[2] Univ Mumbai, Dept Chem, Charitrakar Padma Bhushan Dr Dhananjay Keer Ratnag, Ratnagiri 415639, Maharashtra, India

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2025年 / 61卷 / 01期

关键词：

green synthesis; microwave irradiation; cashew shell extract; aromatic aldehyde; urea; thiourea; ethyl acetoacetate; ONE-POT SYNTHESIS;

D O I：

10.1134/S1070428024602073

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cashew shell extract has been found to be a natural acid catalyst, leading to the development of a straightforward, easy, and environmentally friendly Biginelli synthesis of dihydropyrimidinone/thione derivatives. The Biginelli reaction was conducted in a single step under microwave irradiation and provided outstanding yields in a shorter reaction time. The proposed method may be utilized to create dihydropyrimidinone/thione derivatives on a wide scale due to simple reaction conditions and low cost and availability of the catalyst.

引用

页码：157 / 161

页数：5

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