Spectroflurometric Determination of Adapalene Using Potassium Permanganate as a Reagent in Sea Water, and Wastewater

Over the past few decades, numerous researchers have focused on creating novel, practical, affordable, and easy-to-use techniques for determining and estimating organic pollutants in aquatic environments. This study aims to determine ADP drug using KMnO4 as reagent by spectrofluorometric method. At pH 4, the fluorescence spectrum of the produced complex ion association [Mn (II)-ADP] was obtained at 420 nm with high intensity. The quantification and detection limits were 0.56 and 0.18 mu g mL-1, respectively. The Stern-Volmer and the apparent binding constant were calculated to be 158.6 and 159.95 L mol-1, respectively. Also, different variables were investigated such as KMnO4 concentration, and the optimized conditions were pH 4, and 0.1 mu g mL-1, respectively. In studied samples, adapalene recovery percentages ranged from (90-95%), and (90-93%) in wastewater, and sea water, respectively. These results represent an exceptional and a perfect recovery percentage.