The complex relationship between the microbiota-gut-brain axis and neurodegenerative diseases and future perspectives

被引:0
|
作者
Ying Chen [1 ]
Dongwei Wang [2 ]
Yinsheng Liao [1 ]
Gang Zuo [2 ]
Xiaojun Lu [1 ]
机构
[1] Suzhou Medical College of Soochow University,Department of Neurosurgery
[2] The First People’s Hospital of Taicang,Department of Anesthesiology
[3] Taicang Affiliated Hospital of Soochow University,undefined
[4] The First People’s Hospital of Taicang,undefined
[5] Taicang Affiliated Hospital of Soochow University,undefined
来源
Discover Medicine | / 1卷 / 1期
关键词
Neurodegenerative diseases; Microbiota-gut-brain axis; Gut bacterial community; Metabolites of the bacterial community;
D O I
10.1007/s44337-024-00135-2
中图分类号
学科分类号
摘要
The morbidity and mortality of neurodegenerative diseases (NNDs) are increasing year by year, but the pathogenesis of the diseases is still unclear and the only currently available treatments are very limited. The aging of the world's population is a serious trend, and the search for new treatments is urgent. The discovery of the microbial-gut-brain axis provides new therapeutic ideas. In this paper, we will describe the current mechanism of the microbial-gut-brain axis, and discuss the feasible solutions for the treatment of neurodegenerative diseases by regulating the gut microbiota, in order to provide new ideas for the treatment of neurodegenerative diseases in the future.
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