Eating disorders and disordered eating symptoms in individuals at clinical high risk for psychosis: a systematic review and meta-analysis

被引：1

作者：

Lo Buglio, Gabriele ^{[1
]}

Mirabella, Marta ^{[1
]}

Muzi, Laura ^{[2
]}

Boldrini, Tommaso ^{[3
]}

Cerasti, Erika ^{[4
]}

Bjornestad, Jone ^{[5
,6
,7
]}

Fiorentino, Flavia ^{[1
]}

Polari, Andrea ^{[8
,9
]}

Riccioli, Eleonora ^{[1
]}

Rugo, Michele Angelo ^{[10
]}

Solmi, Marco ^{[11
,12
,13
,14
]}

Lingiardi, Vittorio ^{[1
]}

Tanzilli, Annalisa ^{[1
]}

机构：

[1] Sapienza Univ Rome, Fac Med & Psychol, Dept Dynam & Clin Psychol & Hlth Studies, Rome, Italy

[2] Univ Perugia, Dept Philosophy Social Sci Humanities & Educ, Perugia, Italy

[3] Pegaso Telematic Univ, Dept Psychol & Educ Sci, Naples, Italy

[4] Io Se Posso Komun, Rome, Italy

[5] Univ Stavanger, Fac Social Sci, Dept Social Studies, Stavanger, Norway

[6] Stavanger Univ Hosp, TIPS Network Clin Res Psychosis, Stavanger, Norway

[7] Dist Gen Hosp Forde, Dept Psychiat, Forde, Norway

[8] Orygen Specialist Programs, Melbourne, Australia

[9] Univ Melbourne, Ctr Youth Mental Hlth, Parkville, Vic, Australia

[10] Eating Disorder Clin Residenza Gruber, Bologna, Italy

[11] Univ Ottawa, Dept Psychiat, SCI Lab, Ottawa, ON, Canada

[12] Ottawa Hosp, Dept Mental Hlth, Reg Ctr Treatment Eating Disorders & Track, Champlain Episode Psychosis Program 1, Ottawa, ON, Canada

[13] Univ Ottawa, Ottawa Hosp Res Inst OHRI, Clin Epidemiol Program, Ottawa, ON, Canada

[14] Charite, Dept Child & Adolescent Psychiat, Berlin, Germany

来源：

EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY | 2024年 / 29卷 / 01期

关键词：

Eating disorders; Clinical high risk for psychosis; Prodrome; Psychosis; Meta-analysis; Transdiagnostic approach; CHILDHOOD TRAUMA; QUESTIONNAIRE; RELIABILITY; INTERVIEW; PEOPLE; STATE;

D O I：

10.1007/s40519-024-01708-x

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

BackgroundEating disorders (EDs) are among the least studied mental disorders in individuals at clinical high risk for psychosis (CHR-P). The primary aim (a) of this systematic review and meta-analysis was to identify factors predicting ED diagnoses in CHR-P individuals. The secondary aim (b) was providing a comprehensive clinical description of individuals with both CHR-P and EDs/ED-related symptoms.MethodsPreferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020-compliant systematic review and meta-analysis, searching PubMed/(EBSCO)PsycINFO/Web of Science for studies published between 01/01/2018 and 30/05/2023, including individuals with CHR-P and EDs/ED symptoms (PROSPERO CRD42023488792). Quality assessment was performed using the Newcastle-Ottawa Scale (NOS). We performed a meta-regression model on the proportion of EDs in CHR-P individuals (primary aim) and conducted a narrative synthesis (secondary aim).ResultsWe included 26 articles, reporting on 2,060 and 589 subjects for study aim (a) and (b), respectively (mean NOS score = 6.38). The prevalence of EDs in CHR-P individuals was 0.05 (95% CI 0.3-0.8). No factor had a significant effect on the proportion of EDs in CHR-P individuals. This result is limited by the inability to include ED-related symptoms and antipsychotic prescriptions in the meta-regression model, due to an insufficient number of studies reporting on these variables. The narrative synthesis offers a characterization of individuals with both CHR-P and ED/ED-related symptoms; however, the limited number of included studies is insufficient to support definitive conclusions.ConclusionsNo significant predictor of EDs was found in CHR-P individuals. Transdiagnostic, prospective cohort studies are warranted to examine long-term outcomes in individuals with both CHR-P and EDs, beyond diagnostic silos.Level of evidenceI. Systematic review and meta-analysis

引用

页数：13

共 87 条

[1] Clinical and functional characteristics of youth at clinical high-risk for psychosis who do not transition to psychosis [J].

Addington, Jean ;

Stowkowy, Jacqueline ;

Liu, Lu ;

Cadenhead, Kristin S. ;

Cannon, Tyrone D. ;

Cornblatt, Barbara A. ;

McGlashan, Thomas H. ;

Perkins, Diana O. ;

Seidman, Larry J. ;

Tsuang, Ming T. ;

Walker, Elaine F. ;

Bearden, Carrie E. ;

Mathalon, Daniel H. ;

Santesteban-Echarri, Olga ;

Woods, Scott W. .

PSYCHOLOGICAL MEDICINE, 2019, 49 (10) :1670-1677

[2] Prevalence of non-psychotic disorders in ultra-high risk individuals and transition to psychosis: A systematic review [J].

Albert, Umberto ;

Tomassi, Simona ;

Maina, Giuseppe ;

Tosato, Sarah .

PSYCHIATRY RESEARCH, 2018, 270 :1-12

[3]

American Psychiatric Association, 2022, Diagnostic and statistical manual of mental disorders: DSM-5TM, DOI 10.1176/appi.books.9780890425596

[4]

American Psychiatric Association, 2013, DIAGN STAT MAN MENT, DOI 10.1176/appi.books.9780890425596

[5]

[Anonymous], 2014, Psychosis and schizophrenia in adults: prevention and management

[6] Amygdala subnucleus volumes in psychosis high-risk state and first-episode psychosis [J].

Armio, Reetta-Liina ;

Laurikainen, Heikki ;

Ilonen, Tuula ;

Walta, Maija ;

Salokangas, Raimo K. R. ;

Koutsouleris, Nikolaos ;

Hietala, Jarmo ;

Tuominen, Lauri .

SCHIZOPHRENIA RESEARCH, 2020, 215 :284-292

[7] How to perform a meta-analysis with R: a practical tutorial [J].

Balduzzi, Sara ;

Ruecker, Gerta ;

Schwarzer, Guido .

EVIDENCE-BASED MENTAL HEALTH, 2019, 22 (04) :153-160

[8] Prevention of First-Episode Psychosis in People at Clinical High Risk: A Randomized Controlled, Multicentre Trial Comparing Cognitive-Behavioral Therapy and Clinical Management Plus Low-Dose Aripiprazole or Placebo (PREVENT) [J].

Bechdolf, Andreas ;

Mueller, Hendrik ;

Hellmich, Martin ;

de Millas, Walter ;

Falkai, Peter ;

Gaebel, Wolfgang ;

Gallinat, Juergen ;

Hasan, Alkomiet ;

Heinz, Andreas ;

Janssen, Birgit ;

Juckel, Georg ;

Karow, Anne ;

Krueger-Oezguerdal, Seza ;

Lambert, Martin ;

Maier, Wolfgang ;

Meyer-Lindenberg, Andreas ;

Putzfeld, Verena ;

Rausch, Franziska ;

Schneider, Frank ;

Stuetzer, Hartmut ;

Wobrock, Thomas ;

Wagner, Michael ;

Zink, Mathias ;

Klosterkotter, Joachim .

SCHIZOPHRENIA BULLETIN, 2023, 49 (04) :1055-1066

[9] Clinical utility of the at-risk for psychosis state beyond transition: A multidimensional network analysis [J].

Boldrini, Tommaso ;

Buglio, Gabriele Lo ;

Cerasti, Erika ;

Pontillo, Maria ;

Muzi, Laura ;

Salcuni, Silvia ;

Polari, Andrea ;

Vicari, Stefano ;

Lingiardi, Vittorio ;

Solmi, Marco .

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2025, 34 (01) :287-296

[10] Personality Traits and Disorders in Adolescents at Clinical High Risk for Psychosis: Toward a Clinically Meaningful Diagnosis [J].

Boldrini, Tommaso ;

Tanzilli, Annalisa ;

Di Cicilia, Giuseppe ;

Gualco, Ivan ;

Lingiardi, Vittorio ;

Salcuni, Silvia ;

Tata, Maria Cristina ;

Vicari, Stefano ;

Pontillo, Maria .

FRONTIERS IN PSYCHIATRY, 2020, 11 :1-11

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