Relationship between functional structures and horizontal connections in macaque inferior temporal cortex

被引:0
作者
Hu, Danling [1 ,2 ,3 ]
Sato, Takayuki [4 ,5 ]
Rockland, Kathleen S. [6 ]
Tanifuji, Manabu [4 ,7 ]
Tanigawa, Hisashi [1 ,2 ,3 ,4 ]
机构
[1] Zhejiang Univ, Dept Neurosurg,Affiliated Hosp 2, Interdisciplinary Inst Neurosci & Technol, Sch Med, Hangzhou, Peoples R China
[2] Zhejiang Univ, Coll Biomed Engn & Instrument Sci, Key Lab Biomed Engn Minist Educ, Hangzhou, Peoples R China
[3] Zhejiang Univ, MOE Frontier Sci Ctr Brain Sci & Brain Machine Int, Sch Brain Sci & Brain Med, Hangzhou, Peoples R China
[4] RIKEN Ctr Brain Sci, Lab Integrat Neural Syst, Wako, Saitama, Japan
[5] Fukushima Univ, Commun Future Design Ctr, Fukushima, Japan
[6] Boston Univ, Chobanian & Avedisian Sch Med, Dept Anat & Neurobiol, Boston, MA USA
[7] Waseda Univ, Fac Sci & Engn, Dept Life Sci & Med Biosci, Tokyo, Tokyo, Japan
来源
SCIENTIFIC REPORTS | 2025年 / 15卷 / 01期
基金
国家重点研发计划; 中国国家自然科学基金;
关键词
Intrinsic signal optical imaging; Anterograde tracer; Monkey; Non-human primate; Intrinsic connections; INTRINSIC CONNECTIONS; INFEROTEMPORAL CORTEX; VISUAL-CORTEX; ORIENTATION SELECTIVITY; LATERAL CONNECTIVITY; STRIATE CORTEX; ORGANIZATION; NEURONS; OBJECTS; SPECIFICITY;
D O I
10.1038/s41598-025-87517-3
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Horizontal connections in anterior inferior temporal cortex (ITC) are thought to play an important role in object recognition by integrating information across spatially separated functional columns, but their functional organization remains unclear. Using a combination of optical imaging, electrophysiological recording, and anatomical tracing, we investigated the relationship between stimulus-response maps and patterns of horizontal axon terminals in the macaque ITC. In contrast to the "like-to-like" connectivity observed in the early visual cortex, we found that horizontal axons in ITC do not preferentially connect sites with similar object selectivity. While some axon terminal patches shared responsiveness to specific visual features with the injection site, many connected to regions with different selectivity. Our results suggest that horizontal connections in anterior ITC exhibit diverse functional connectivity, potentially supporting flexible integration of visual information for advanced object recognition processes.
引用
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页数:15
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