Postoperative outcomes and wound events in incisional hernia repair using hybrid mesh: results from a prospective multicenter italian study

被引:0
作者
Pizza, Francesco [1 ]
Iuppa, Antonio [2 ]
Maida, Pietro [3 ]
Pilone, Vincenzo [4 ]
Crucitti, Antonio [5 ]
Carmen, Tomaiuolo Pasquina Maria [5 ]
Morini, Lorenzo [6 ]
Marin, Jacopo Nicolo [6 ]
Petitti, Tommaso [7 ]
Bertoglio, Camillo [8 ]
Marte, Gianpaolo [9 ]
Sordelli, Ignazio [3 ]
Gili, Simona [10 ]
Lucido, Francesco Saverio [11 ]
Busciano, Lugi [11 ]
D'Antonio, Dario [1 ]
Docimo, Ludovico [11 ]
Gambardella, Claudio [11 ]
机构
[1] Hosp Rizzoli, Asl Nord Dept Surg Napoli2, Naples, Italy
[2] Mediterranean Oncol Inst, Div Surg, Catania, Italy
[3] Casa Cura Privata Malzoni, Surg Avellino, Campania, Italy
[4] Univ Naples Federico II, Dept Publ Hlth, AOU Federico II, Via S Pansini 5, Naples, Italy
[5] UOC Chirurg Gen 1, Fdn Policlin Univ Agostino Gemelli, IRCCS Univ Cattolica Sacro Cuore, Rome, Italy
[6] ASST Grande Osped Metropolitano Niguarda, Div Gen & Oncol Surg, Milan, Italy
[7] Surg Hosp San Severo Foggia, Div Gen, San Severo, Italy
[8] Hosp Magenta, Div Gen Surg, ASST Ovest Milanese, I-20013 Magenta, Italy
[9] Osped Mare, Div Gen Surg, Naples, Italy
[10] Hosp San Leonardo, Asl Sud Dept Surg Napoli3, Castellammare, Italy
[11] Campania Luigi Vanvitelli, Italy Gen Mininvas & Bariatr Surg 3Div, Naples, Italy
关键词
Hybrid mesh; Incisional hernia; IPOM plus; IPOM standard; CLOSURE; DEFECT;
D O I
10.1007/s10029-025-03285-z
中图分类号
R61 [外科手术学];
学科分类号
摘要
Purpose The complexity of managing ventral hernias leads surgeons to explore different optimal techniques and mesh selection. Hybrid meshes, combining absorbable and permanent components, aim to balance long-term durability and infection risk. This study evaluated the extended-term outcomes of GORE (R) SYNECOR intraperitoneal (IP) biomaterial for incisional hernia repair through minimally invasive laparoscopic techniques. Methods Conducted across eight Italian surgery centers from January 2020 to September 2022, this multicenter analysis prospectively assessed the outcomes of patients undergoing laparoscopic repair of incisional hernias using GORE (R) SYNECOR. Outcomes included postoperative wound events, pain, recurrence, and mesh bulging. Results A total of 371 patients participated in the study. No serious adverse events or significant mesh-related complications were observed. Surgical site occurrences (SSO) were recorded in a proportion of cases, and hernia sac volume was identified as the only independent risk factor (p < 0.0001). At three months post-surgery, pain levels and impacts on daily activities were minimal. At 24 months, recurrence and mesh bulging were associated only with patients with hernia sac sizes larger than 450 cm3. Conclusion Laparoscopic incisional hernia repair using GORE (R) SYNECOR hybrid mesh demonstrated satisfactory safety and efficacy regarding wound-related events and recurrence. Minor complications were more closely related to hernia sac size rather than the surgical approach, suggesting that the laparoscopic technique may optimize outcomes, particularly in elderly, smokers, and overweight patients.
引用
收藏
页数:14
相关论文
共 50 条
[41]   A randomised, multi-centre, prospective, observer and patient blind study to evaluate a non-absorbable polypropylene mesh vs. a partly absorbable mesh in incisional hernia repair [J].
A. Rickert ;
P. Kienle ;
A. Kuthe ;
P. Baumann ;
R. Engemann ;
J. Kuhlgatz ;
M. von Frankenberg ;
H. P. Knaebel ;
M. W. Büchler .
Langenbeck's Archives of Surgery, 2012, 397 :1225-1234
[42]   A randomised, multi-centre, prospective, observer and patient blind study to evaluate a non-absorbable polypropylene mesh vs. a partly absorbable mesh in incisional hernia repair [J].
Rickert, A. ;
Kienle, P. ;
Kuthe, A. ;
Baumann, P. ;
Engemann, R. ;
Kuhlgatz, J. ;
von Frankenberg, M. ;
Knaebel, H. P. ;
Buechler, M. W. .
LANGENBECKS ARCHIVES OF SURGERY, 2012, 397 (08) :1225-1234
[43]   Risk factors for incisional hernia according to different wound sites after open hepatectomy using combinations of vertical and horizontal incisions: A multicenter cohort study [J].
Iida, Hiroya ;
Tani, Masaji ;
Hirokawa, Fumitoshi ;
Ueno, Masaki ;
Noda, Takehiro ;
Takemura, Shigekazu ;
Nomi, Takeo ;
Nakai, Takuya ;
Kaibori, Masaki ;
Kubo, Shoji .
ANNALS OF GASTROENTEROLOGICAL SURGERY, 2021, 5 (05) :701-710
[44]   Functional outcomes in symptomatic versus asymptomatic patients undergoing incisional hernia repair: Replacing one problem with another? A prospective cohort study in 1312 patients [J].
de Smet, Gijs H. J. ;
Sneiders, Dimitri ;
Yurtkap, Yagmur ;
Menon, Anand G. ;
Jeekel, Johannes ;
Kleinrensink, Gert-Jan ;
Lange, Johan F. ;
Gillion, Jean-Francois .
INTERNATIONAL JOURNAL OF SURGERY, 2020, 82 :76-84
[45]   Prospective, multicenter study of P4HB (Phasix™) mesh for hernia repair in cohort at risk for complications: 3-Year follow-up [J].
Roth, John Scott ;
Anthone, Gary J. ;
Selzer, Don J. ;
Poulose, Benjamin K. ;
Pierce, Richard A. ;
Bittner, James G. ;
Hope, William W. ;
Dunn, Raymond M. ;
Martindale, Robert G. ;
Goldblatt, Matthew I. ;
Earle, David B. ;
Romanelli, John R. ;
Mancini, Gregory J. ;
Greenberg, Jacob A. ;
Linn, John G. ;
Parra-Davila, Eduardo ;
Sandler, Bryan J. ;
Deeken, Corey R. ;
Verbarg, Jasenka ;
Salluzzo, Jennifer L. ;
Voeller, Guy R. .
ANNALS OF MEDICINE AND SURGERY, 2021, 61 :1-7
[46]   A randomised, multi-centre, prospective, double blind pilot-study to evaluate safety and efficacy of the non-absorbable Optilene® Mesh Elastic versus the partly absorbable Ultrapro® Mesh for incisional hernia repair [J].
Christoph Seiler ;
Petra Baumann ;
Peter Kienle ;
Andreas Kuthe ;
Jens Kuhlgatz ;
Rainer Engemann ;
Moritz v Frankenberg ;
Hanns-Peter Knaebel .
BMC Surgery, 10
[47]   Short-term Outcomes for Open and Laparoscopic Midline Incisional Hernia Repair A Randomized Multicenter Controlled Trial: The ProLOVE (Prospective Randomized Trial on Open Versus Laparoscopic Operation of Ventral Eventrations) Trial [J].
Rogmark, Peder ;
Petersson, Ulf ;
Bringman, Sven ;
Eklund, Arne ;
Ezra, Emmanuel ;
Sevonius, Dan ;
Smedberg, Sam ;
Osterberg, Johanna ;
Montgomery, Agneta .
ANNALS OF SURGERY, 2013, 258 (01) :37-45
[48]   Incisional hernia repair after kidney transplantation in a tertiary high-volume center: outcomes from a 10-year retrospective cohort study [J].
Gianluca Cassese ;
Antonio Castaldi ;
Bader Al Taweel ;
Moglie Le Quintrec ;
Rodolphe Thuret ;
Francis Navarro ;
Fabrizio Panaro .
International Urology and Nephrology, 2022, 54 :525-531
[49]   Incisional hernia repair after kidney transplantation in a tertiary high-volume center: outcomes from a 10-year retrospective cohort study [J].
Cassese, Gianluca ;
Castaldi, Antonio ;
Al Taweel, Bader ;
Le Quintrec, Moglie ;
Thuret, Rodolphe ;
Navarro, Francis ;
Panaro, Fabrizio .
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2022, 54 (03) :525-531
[50]   Impact of antimicrobial prophylaxis duration on wound infection in mesh repair of incisional hernia – preliminary results of a prospective randomized trialAuswirkung der Dauer der antimikrobiellen Prophylaxe auf Wundinfektionen bei der Netzreparation von Narbenhernien – vorläufige Ergebnisse einer prospektiven randomisierten Untersuchung [J].
A. Becker ;
L. Koltun ;
J. Sayfan .
European Surgery, 2008, 40 (1) :37-40