ZDHHC20 mediated S-palmitoylation of fatty acid synthase (FASN) promotes hepatocarcinogenesis

被引：0
|
作者：
Yaqi Mo [1 ]
Yamei Han [2 ]
Yang Chen [2 ]
Chunling Fu [3 ]
Qing Li [4 ]
Zhuang Liu [1 ]
Mingming Xiao [2 ]
Bo Xu [2 ]
机构：
[1] Center for Intelligent Oncology,Department of Biochemistry and Molecular Biology, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy
[2] Chongqing University Cancer Hospital and Chongqing University School of Medicine,Department of Radiation Oncology
[3] and Chongqing Key Laboratory of Intelligent Oncology for Breast Cancer,Department of Pathology
[4] Tianjin Medical University Cancer Institute and Hospital,Department of Pancreatic Surgery
[5] National Clinical Research Center for Cancer,undefined
[6] Tianjin Medical University Cancer Institute and Hospital,undefined
[7] Chongqing University Cancer Hospital,undefined
[8] Fudan University Shanghai Cancer Center,undefined
来源：
Molecular Cancer | / 23卷 / 1期
关键词：
Hepatocarcinogenesis; S-palmitoylation; ZDHHC20; FASN;
D O I：
10.1186/s12943-024-02195-5
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 32 条
  • [1] zDHHC20-mediated S-palmitoylation of KAP1 promotes DNA damage repair and enhances radioresistance
    Liu, Zhuang
    Xiao, Mingming
    Wang, Han
    Xu, Bo
    RADIOTHERAPY AND ONCOLOGY, 2024, 194 : S5379 - S5381
  • [2] Research progress on S-palmitoylation modification mediated by the ZDHHC family in glioblastoma
    Tang, Beiyan
    Kang, Wei
    Dong, Qiang
    Qin, Zhenwei
    Duan, Lei
    Zhao, Xianjun
    Yuan, Guoqiang
    Pan, Yawen
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2024, 12
  • [3] ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity
    Baoen Chen
    Baohui Zheng
    Michael DeRan
    Gopala K Jarugumilli
    Jianjun Fu
    Yang S Brooks
    Xu Wu
    Nature Chemical Biology, 2016, 12 : 686 - 693
  • [4] ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity
    Chen, Baoen
    Zheng, Baohui
    DeRan, Michael
    Jarugumilli, Gopala K.
    Fu, Jianjun
    Brooks, Yang S.
    Wu, Xu
    NATURE CHEMICAL BIOLOGY, 2016, 12 (09) : 686 - +
  • [5] zDHHC-Mediated S-Palmitoylation in Skin Health and Its Targeting as a Treatment Perspective
    Abdulrahman, Farah A.
    Benford, King A.
    Lin, Gregory T.
    Maroun, Andrew J.
    Sammons, Caleb
    Shirzad, Darya N.
    Tsai, Harrison
    Van Brunt, Vincent L.
    Jones, Zack
    Marquez, Jafet E.
    Ratkus, Evan C.
    Shehadeh, Abdulrahman K.
    Abasto Valle, Hugo
    Fejzo, Dea
    Gilbert, Ashlynn E.
    Mcwee, Catherine A.
    Underwood, Lexie F.
    Indico, Ethny
    Rork, Brittany B.
    Nanjundan, Meera
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2025, 26 (04)
  • [6] ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma
    Wang, Yang
    Shen, Na
    Yang, Yang
    Xia, Yuan
    Zhang, Wenhao
    Lu, Yu
    Wang, Zhicheng
    Yang, Ze
    Wang, Zhangjie
    CELL COMMUNICATION AND SIGNALING, 2024, 22 (01)
  • [7] ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma
    Yang Wang
    Na Shen
    Yang Yang
    Yuan Xia
    Wenhao Zhang
    Yu Lu
    Zhicheng Wang
    Ze Yang
    Zhangjie Wang
    Cell Communication and Signaling, 22
  • [8] ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression
    Zhang, Huan
    Sun, Yan
    Wang, Zhaokai
    Huang, Xiaoju
    Tang, Lu
    Jiang, Ke
    Jin, Xin
    NATURE COMMUNICATIONS, 2024, 15 (01)
  • [9] ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression
    Meng Yuan
    Xiaobing Chen
    Yitang Sun
    Li Jiang
    Zhongni Xia
    Kaixiong Ye
    Hong Jiang
    Bo Yang
    Meidan Ying
    Ji Cao
    Qiaojun He
    ActaPharmaceuticaSinicaB, 2020, 10 (08) : 1426 - 1439
  • [10] zDHHC20-driven S-palmitoylation of CD80 is required for its costimulatory function
    Lu, Bin
    Sun, Yi-yun
    Chen, Bo-ya
    Yang, Bo
    He, Qiao-jun
    Li, Jun
    Cao, Ji
    ACTA PHARMACOLOGICA SINICA, 2024, 45 (06) : 1214 - 1223
1234