Successful treatment of an anti-MDA5 antibody-positive Juvenile Dermatomyositis patient with refractory interstitial lung disease using tofacitinib

被引：0

作者：

Natoli, Valentina ^{[1
,2
]}

Palmeri, Serena ^{[1
]}

Rebollo-Gimenez, Ana Isabel ^{[1
,3
]}

Matucci-Cerinic, Caterina ^{[1
,2
]}

Bocca, Paola ^{[2
]}

Caorsi, Roberta ^{[2
]}

Volpi, Stefano ^{[1
,2
]}

Papa, Riccardo ^{[2
]}

Consolaro, Alessandro ^{[1
,2
]}

Gattorno, Marco ^{[2
]}

Ravelli, Angelo ^{[1
,4
]}

Rosina, Silvia ^{[2
]}

机构：

[1] Univ Studi Genova, Dipartimento Neurosci Riabilitaz Oftalmol Genet &, Genoa, Italy

[2] IRCCS Ist Giannina Gaslini, Paediat Rheumatol & Autoinflammatory Dis Unit, Genoa, Italy

[3] Hosp Univ Principe Asturias, Madrid, Spain

[4] IRCCS Ist Giannina Gaslini, Direz Sci, Genoa, Italy

来源：

PEDIATRIC RHEUMATOLOGY | 2025年 / 23卷 / 01期

关键词：

Juvenile dermatomyositis; Anti-MDA5; antibodies; Interstitial lung disease; Tofacitinib; JAK inhibitors; Type I IFN gene signature;

D O I：

10.1186/s12969-024-01044-5

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

引用

页数：5

共 5 条

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[2] Tofacitinib for refractory interstitial lung diseases in anti-melanoma differentiation-associated 5 gene antibody-positive dermatomyositis [J].

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[3]

Paik JJ, 2023, CLIN EXP RHEUMATOL, V41, P348, DOI 10.55563/clinexprheumatol/hxin6o

[4] Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care [J].

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NATURE REVIEWS RHEUMATOLOGY, 2023, 19 (06) :343-362

[5] Tofacitinib for new-onset adult patients with anti-melanoma differentiation-associated 5 gene antibody positive dermatomyositis [J].

Wang, Yanhua ;

Luo, Jing ;

Lv, Xiaohong ;

Li, Yuanyuan ;

An, Qi ;

Mo, Lingfei ;

Hu, Nan ;

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CLINICAL RHEUMATOLOGY, 2023, 42 (07) :1847-1853

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