Use of hydroxyurea in French-speaking Sub-Saharan Africa

被引：0

作者：

Arlet, Jean-Benoit ^{[1
,2
]}

Bernaudin, Francoise ^{[3
]}

Deme-Ly, Indou ^{[4
,5
]}

Coulibaly, Binta

Corbasson, Anne ^{[1
]}

Diagne, Ibrahima ^{[6
]}

Diallo, Dapa ^{[7
,8
]}

Diop, Saliou ^{[9
]}

Eposse, Charlotte ^{[10
]}

Galacteros, Frederic ^{[11
,12
]}

Hermine, Olivier ^{[13
]}

Kafando, Eleonore ^{[14
]}

Laine, Agnes ^{[15
]}

de Montalembert, Mariane ^{[16
]}

Vodouhe, Constant ^{[17
]}

Vovor, Ahoefa ^{[18
]}

Ranque, Brigitte ^{[1
,2
]}

Tshilolo, Leon ^{[19
]}

机构：

[1] Georges Pompidou European Hosp, AP HP, French Natl Reference Ctr Sickle Cell Anemia Thala, Dept Internal Med, Paris, France

[2] Univ Paris Cite, Paris, France

[3] Intercommunal Hosp Creteil, Sickle Cell Referral Ctr, Pediat Dept, F-94000 Creteil, France

[4] Cheikh Anta Diop Univ, Dakar, Senegal

[5] Albert Royer Natl Children Hosp, Dakar, Senegal

[6] Gaston Berger Univ St Louis, Cooperat & Pedag Innovat, St Louis, Senegal

[7] Univ Sci Tech & Technol Bamako USTTB, Fac Med & Odontostomatol, Hematol, Bamako, Mali

[8] Ctr Res & Control Sickle Cell Dis CRLD, Bamako, Mali

[9] Univ Cheikh Anta Diop, Dept Hematol, Dakar, Senegal

[10] Univ Douala, Douala Laquintinie Hosp, Fac Med & Pharmaceut Sci, Douala, Cameroon

[11] GHU Henri Mondor, AP HP, Unite Malad Genet Globule Rouge UMGGR, Paris, France

[12] U PEC, Med Interne, Paris, France

[13] Necker Enfants Malad Hosp, AP HP, Dept Hematol, Paris, France

[14] Univ Joseph Ki Zerbo, Lab Hematol, Ouagadougou, Burkina Faso

[15] Inst Mondes Africains, Aubervilliers, France

[16] Hop Necker Enfants Malad, Assistance Publ Hop Paris, Serv Pediat Gen, Paris, France

[17] Assoc DORYS, Strasbourg, France

[18] Fac Hlth Sci, Lome, Togo

[19] Ctr Hosp Monkole, Dept Pediat, Kinshasa, DEM REP CONGO

来源：

ANNALS OF HEMATOLOGY | 2025年 / 104卷 / 02期

关键词：

Sickle cell disease; Africa; French-speaking countries; Guidelines; Hydroxyurea;

D O I：

10.1007/s00277-024-06180-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The hydroxyurea is a save, affordable and essential medicine for sickle cell disease (SCD), reducing painful crises and mortality. To foster the prescription of hydroxyurea for patients with SCD in sub-Saharan African countries, the scientific advisory board of Drep.Afrique, a non-governmental organization dedicated to SCD in Africa, has developed a therapeutic guideline well suited to conditions on the ground. These guidelines answer three essential questions: which patients should be prioritized for treatment with hydroxyurea, which dose should be used, and what follow-up should be implemented in those low-resources countries?The guidelines are given as in a concise document for easy use by practitioners on the ground, available in English and in French.

引用

页码：937 / 941

页数：5

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