Electroencephalographic Features of Alcohol Use Disorders with Different Decision-Making Efficiency in Risk Conditions

Abstract: In order to identify the neurophysiological mechanisms underlying the violation of decision-making in risk conditions, we conducted a comparative analysis of spectral EEG indicators of patients with alcohol use disorders with different effectiveness of their decision-making in several cognitive tasks. As a result of the cluster analysis, two subgroups of patients were identified: with “moderate” and with “pronounced” decision-making deficit, which did not differ in socio–demographic and clinical indicators (p > 0.05). The subgroup of patients with a “pronounced” decision-making deficit differed statistically significantly lower values of the spectral power of θ- and α-rhythm in the central (p = 0.018 for θ-rhythm and p = 0.017 for α-rhythm), parietal (p = 0.031 for θ-rhythm and p = 0.014 for α-rhythm), occipital (p = 0.029 for θ-rhythm and p = 0.016 for α-rhythm) and temporal (p = 0.022 on the left and p = 0.043 on the right for α-rhythm) leads compared with patients with “moderate” decision-making deficit. Thus, in a subgroup of patients with a “pronounced” deficit of decision-making, a certain deficit of the brain’s inhibitory systems was noted. © Pleiades Publishing, Inc. 2024.