Characterising the asynchronous resurgence of common respiratory viruses following the COVID-19 pandemic

被引：5

作者：

Zhao, Chenkai ^{[1
]}

Zhang, Tiantian ^{[1
]}

Guo, Ling ^{[1
]}

Sun, Shiqi ^{[1
]}

Miao, Yumeng ^{[1
]}

Yung, Chee Fu ^{[2
,3
,4
]}

Tomlinson, Jane ^{[5
]}

Stolyarov, Kirill ^{[6
]}

Shchomak, Zakhar ^{[7
]}

Poovorawan, Yong ^{[8
]}

Nokes, David James ^{[9
]}

Munoz-Almagro, Carmen ^{[10
,11
,12
]}

Mandelboim, Michal ^{[13
,14
]}

Keck, James W. ^{[15
]}

Langley, Joanne Marie ^{[16
,17
]}

Heikkinen, Terho ^{[18
,19
]}

Deng, Jikui ^{[20
]}

Colson, Philippe ^{[21
,22
,23
]}

Chakhunashvili, Giorgi ^{[24
]}

Caballero, Mauricio T. ^{[25
,26
]}

Bont, Louis ^{[27
,28
,29
]}

Feikin, Daniel R. ^{[30
]}

Nair, Harish ^{[1
,31
]}

Wang, Xin ^{[31
,32
]}

Li, You ^{[1
,31
,33
]}

机构：

[1] Nanjing Med Univ, Sch Publ Hlth, Dept Epidemiol, Natl Vaccine Innovat Platform, Nanjing, Peoples R China

[2] KK Womens & Childrens Hosp, Dept Paediat, Infect Dis Serv, Singapore, Singapore

[3] Duke NUS Med Sch, Singapore, Singapore

[4] Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore, Singapore

[5] Royal Childrens Hosp Melbourne, Infect Prevent & Control Dept, Melbourne, Vic, Australia

[6] Smorodintsev Res Inst Influenza, St Petersburg, Russia

[7] Ctr Hosp Univ Lisboa Norte, Hosp Santa Maria, Dept Pediat, Lisbon, Portugal

[8] Chulalongkorn Univ, Fac Med, Ctr Excellence Clin Virol, Bangkok, Thailand

[9] Kemri Wellcome Trust Res Programme, Kilifi, Kenya

[10] Hosp St Joan Deu, Inst Recerca St Joan Deu IRSJD, Barcelona, Spain

[11] CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain

[12] Univ Int Catalunya, Dept Med, Barcelona, Spain

[13] Minist Hlth, Cent Virol Lab, Tel Hashomer, Israel

[14] Tel Aviv Univ, Fac Med, Tel Aviv, Israel

[15] Alaska Native Tribal Hlth Consortium, Res Serv Dept, Anchorage, AK USA

[16] Dalhousie Univ, IWK Hlth & Nova Scotia Hlth, Canadian Ctr Vaccinol, Halifax, NS, Canada

[17] Dalhousie Univ, Dept Pediat Community Hlth & Epidemiol, Halifax, NS, Canada

[18] Univ Turku, Dept Pediat, Turku, Finland

[19] Turku Univ Hosp, Dept Pediat, Turku, Finland

[20] Shenzhen Childrens Hosp, Dept Infect Dis, Shenzhen, Peoples R China

[21] IHU Mediterranee Infect, Infect Dis Dept, Marseille, France

[22] Aix Marseille Univ, Inst Rech Dev IRD, Microbes Evolut Phylogeny & Infect MEPHI, Marseille, France

[23] AP HM, Marseille, France

[24] Natl Ctr Dis Control & Publ Hlth, Tbilisi, Georgia

[25] Consejo Nacl Invest Cient & Tecn CONICET, Buenos Aires, DF, Argentina

[26] Univ Nacl San Martin UNSAM, Escuela Bio & Nanotecnol EByN, Ctr INFANT Med Traslac CIMET, Buenos Aires, DF, Argentina

[27] Univ Med Ctr Utrecht, Wilhemina Childrens Hosp, Dept Pediat, Utrecht, Netherlands

[28] ReSViNET Fdn, Zeist, Netherlands

[29] Yale Univ, Yale Sch Publ Hlth, Dept Epidemiol Microbial Dis, New Haven, CT USA

[30] WHO, Dept Immunizat Vaccines & Biol, Geneva, Switzerland

[31] Univ Edinburgh, Usher Inst, Ctr Global Hlth, Edinburgh, Midlothian, Scotland

[32] Nanjing Med Univ, Sch Publ Hlth, Dept Biostat, Natl Vaccine Innovat Platform, Nanjing, Peoples R China

[33] Nanjing Med Univ, Changzhou Peoples Hosp 3, Changzhou Med Ctr, Changzhou, Peoples R China

来源：

NATURE COMMUNICATIONS | 2025年 / 16卷 / 01期

基金：

中国国家自然科学基金;

关键词：

UNITED-STATES; RHINOVIRUS; ILLNESSES; INFLUENZA; CHILDREN;

D O I：

10.1038/s41467-025-56776-z

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The COVID-19 pandemic and relevant non-pharmaceutical interventions (NPIs) interrupted the circulation of common respiratory viruses. These viruses demonstrated an unprecedented asynchronous resurgence as NPIs were relaxed. We compiled a global dataset from a systematic review, online surveillance reports and unpublished data from Respiratory Virus Global Epidemiology Network, encompassing 92 sites. We compared the resurgence timings of respiratory viruses within each site and synthesised differences in timings across sites, using a generalised linear mixed-effects model. We revealed a distinct sequential timing in the first post-pandemic resurgence: rhinovirus resurged the earliest, followed by seasonal coronavirus, parainfluenza virus, respiratory syncytial virus, adenovirus, metapneumovirus and influenza A virus, with influenza B virus exhibiting the latest resurgence. Similar sequential timing was observed in the second resurgence except influenza A virus caught up with metapneumovirus. The consistent asynchrony across geographical regions suggests that virus-specific characteristics, rather than location-specific factors, determining the relative timing of resurgence.

引用

页数：11

共 48 条

[1] Very little influenza in the WHO European Region during the 2020/21 season, weeks 40 2020 to 8 2021 [J].

Adlhoch, Cornelia ;

Mook, Piers ;

Lamb, Favelle ;

Ferland, Lisa ;

Melidou, Angeliki ;

Amato-Gauci, Andrew J. ;

Pebody, Richard .

EUROSURVEILLANCE, 2021, 26 (11) :2-9

[2] Occurrence of multiple respiratory viruses in wastewater in Queensland, Australia: Potential for community disease surveillance [J].

Ahmed, Warish ;

Bivins, Aaron ;

Stephens, Mikayla ;

Metcalfe, Suzanne ;

Smith, Wendy J. M. ;

Sirikanchana, Kwanrawee ;

Kitajima, Masaaki ;

Simpson, Stuart L. .

SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 864

[3] National and regional modeling of distinct RSV seasonality thresholds for antigen and PCR testing in the United States [J].

Ambrose, Christopher S. ;

Steed, Lisa L. ;

Brandon, Mike ;

Frye, Kara ;

Olajide, Ifedapo R. ;

Thomson, Gina .

JOURNAL OF CLINICAL VIROLOGY, 2019, 120 :68-77

[4] Transmission route of rhinovirus- the causative agent for common cold. A systematic review [J].

Andrup, Lars ;

Krogfelt, Karen A. ;

Hansen, Kristian Schultz ;

Madsen, Anne Mette .

AMERICAN JOURNAL OF INFECTION CONTROL, 2023, 51 (08) :938-957

[5] Rhinoviruses and Their Receptors [J].

Basnet, Sarmila ;

Palmenberg, Ann C. ;

Gern, James E. .

CHEST, 2019, 155 (05) :1018-1025

[6] Microorganisms Associated With Pneumonia in Children <5 Years of Age in Developing and Emerging Countries: The GABRIEL Pneumonia Multicenter, Prospective, Case-Control Study [J].

Benet, Thomas ;

Picot, Valentina Sanchez ;

Messaoudi, Melina ;

Chou, Monidarin ;

Eap, Tekchheng ;

Wang, Jianwei ;

Shen, Kunling ;

Pape, Jean-William ;

Rouzier, Vanessa ;

Awasthi, Shally ;

Pandey, Nitin ;

Bavdekar, Ashish ;

Sanghavi, Sonali ;

Robinson, Annick ;

Rakoto-Andrianarivelo, Mala ;

Sylla, Maryam ;

Diallo, Souleymane ;

Nymadawa, Pagbajabyn ;

Naranbat, Nymadawaagiin ;

Russomando, Graciela ;

Basualdo, Wilma ;

Komurian-Pradel, Florence ;

Endtz, Hubert ;

Vanhems, Philippe ;

Paranhos-Baccala, Glaucia .

CLINICAL INFECTIOUS DISEASES, 2017, 65 (04) :604-612

[7] Wastewater concentrations of human influenza, metapneumovirus, parainfluenza, respiratory syncytial virus, rhinovirus, and seasonal coronavirus nucleic-acids during the COVID-19 pandemic: a surveillance study [J].

Boehm, Alexandria B. ;

Hughes, Bridgette ;

Duong, Dorothea ;

Chan-Herur, Vikram ;

Buchman, Anna ;

Wolfe, Marlene K. ;

White, Bradley J. .

LANCET MICROBE, 2023, 4 (05) :E340-E348

[8]

Canada P. H. A., 2012, Respiratory Virus Detections in Canada

[9] Rhinoviruses delayed the circulation of the pandemic influenza A (H1N1) 2009 virus in France [J].

Casalegno, J. S. ;

Ottmann, M. ;

Duchamp, M. Bouscambert ;

Escuret, V. ;

Billaud, G. ;

Frobert, E. ;

Morfin, F. ;

Lina, B. .

CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (04) :326-329

[10]

Centers for Disease Control and Prevention, 2023, The National Respiratory and Enteric Virus Surveillance System (NREVSS). Interactive Dashboard

← 1 2 3 4 5 →